News tagged with osteoblasts

Mechanical stimuli control bone development

Researchers from ETH Zurich have successfully demonstrated, for the first time in vivo, how bone tissue responds to local mechanical stimuli that control bone formation. The study reveals how important it is to stimulate ...

Sep 02, 2013
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Novel treatment for bone marrow cancer

Multiple myeloma is a form of cancer in which the plasma cells in the bone marrow grow out of control, causing damage to bones as well as predisposing patients to anaemia, infection and kidney failure. A medical procedure ...

Mar 07, 2013
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Osteoblast

Osteoblasts (from the Greek words for "bone" and "germ" or embryonic) are mononucleate cells that are responsible for bone formation; in essence, osteoblasts are specialized fibroblasts that in addition to fibroblastic products, express bone sialoprotein and osteocalcin.

Osteoblasts produce a matrix of osteoid, which is composed mainly of Type I collagen. Osteoblasts are also responsible for mineralization of this matrix. Zinc, copper and sodium are some of the minerals required in this process. Bone is a dynamic tissue that is constantly being reshaped by osteoblasts, in charge of production of matrix and mineral, and osteoclasts, which remodel the tissue. Osteoblast cells tend to decrease with age, affecting the balance of formation and resorption in the bone tissue.

This text uses material from Wikipedia, licensed under CC BY-SA

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