Bone-dissolving cells called osteoclasts are derived from a type of immune cells called macrophages. They are necessary for the maintenance and renewal of bones. But the intracellular mechanisms through which macrophages ...
Jun 10, 2020
0
3
Melatonin could be a novel drug for preventing bone loss to astronauts during space flight. Here we used goldfish scales as a bone model of coexisting osteoclasts and osteoblasts and demonstrated that melatonin synthesis ...
Sep 3, 2019
0
3
Bone homeostasis requires precise balance between deposition of new bone by osteoblasts and resorption of old bone by osteoclasts. Bone diseases, including osteoporosis and rheumatoid arthritis, are the result of increased ...
Dec 9, 2013
0
0
The building blocks of a structure consist of load-bearing elements that rarely change despite renovations or repairs. They remain intact and consistent over time, but in the human body, our building blocks do just the opposite.
Sep 12, 2022
0
77
Osteonecrosis of the jaw is a debilitating and painful condition in which oral lesions develop in individuals taking drugs such as bisphosphonate or denosumab, which are commonly used in treatments for osteoporosis and for ...
Nov 25, 2014
0
0
Bone cancer-related fractures and pain can be reduced by drug treatment, but no one drug is superior, according to a review published in The Cochrane Library. Researchers undertook a systematic review of the current evidence ...
May 15, 2012
0
0
Researchers from ETH Zurich have successfully demonstrated, for the first time in vivo, how bone tissue responds to local mechanical stimuli that control bone formation. The study reveals how important it is to stimulate ...
Sep 2, 2013
0
0
Osteoporosis is a medical condition that causes bones to become fragile and brittle. It is a major health problem worldwide, mainly affecting adults. However, children can also rarely be affected as a result of other diseases ...
Feb 1, 2019
0
0
An existing drug that targets senescent, or sleeping cells could provide the answer to treating lower back pain, according to a new study.
Nov 14, 2023
0
1
The skeleton is constantly being remodelled by the breakdown of old bone by cells called osteoclasts and the formation of new bone by cells called osteoblasts. This coordinated activity is essential for maintaining healthy ...
Dec 4, 2013
0
0
