BRCA1 and BRCA2 ("BReast CAncer genes") are critical tumor suppressor genes—women carrying a mutation in one of these genes have up to an 80 percent risk of developing breast cancer and a 50 percent risk of developing ovarian ...
Jan 24, 2019
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Despite months of aggressive treatment involving surgery and chemotherapy, about 85 percent of women with high-grade wide-spread ovarian cancer will have a recurrence of their disease. This leads to further treatment, but ...
Sep 20, 2018
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Patterns of genetic mutation in ovarian cancer are helping make sense of the disease, and could be used to personalise treatment in future.
Aug 14, 2018
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The tumor suppressor protein ARID1A controls global transcription in ovarian epithelial cells, according to new research conducted at The Wistar Institute, which provided mechanistic insight into tumorigenesis mediated by ...
Jun 26, 2018
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Scientists at the Ovarian Cancer Action Research Centre at Imperial College London have discovered a mechanism that deactivates ovarian cancer cells.
Jun 19, 2018
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Fuyuhiko Tamanoi of Kyoto University's Institute for Integrated Cell-Material Sciences (iCeMS) and colleagues in the U.S. succeeded in establishing a powerful and convenient model to analyse human cancer.
Jun 4, 2018
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In order to spread their destruction, ovarian cancer cells must break free from their tumor home, travel through the fluid in the peritoneal cavity and attach to the outside of the abdominal organs—surfaces that are, by ...
May 8, 2018
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Tagworks Pharmaceuticals, based at Radboud University Medical Center, has developed a new technique for the targeted delivery of chemotherapy for tumors in difficult cases. By way of controlled 'click-to-release' of the chemotherapy ...
May 4, 2018
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A new discovery opens the possibility of developing a novel way to fight ovarian cancer. Researchers at Baylor College of Medicine and the University of Texas MD Anderson Cancer Center have revealed a previously unknown cellular ...
Mar 28, 2018
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Johns Hopkins Kimmel Cancer Center researchers demonstrated that mice with ovarian cancer that received drugs to reactivate dormant genes along with other drugs that activate the immune system had a greater reduction of tumor ...
Dec 5, 2017
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