Newly discovered trigger of Parkinson's upends common beliefs
A new Northwestern Medicine study challenges a common belief in what triggers Parkinson's disease.
Sep 15, 2023
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A new Northwestern Medicine study challenges a common belief in what triggers Parkinson's disease.
Sep 15, 2023
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While mitochondria play a crucial role in producing the energy our cells need to carry out their various functions, when damaged, they can have profound effects on cellular function and contribute to the development of various ...
Jun 27, 2023
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According to a study by The Wistar Institute, the tumor suppressor Parkin, whose levels are reduced in different cancer types, causes acute metabolic and oxidative stress, suppresses mitochondrial trafficking, and blocks ...
Aug 25, 2021
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When cells are stressed, chemical alarms go off, setting in motion a flurry of activity that protects the cell's most important players. During the rush, a protein called Parkin hurries to protect the mitochondria, the power ...
Apr 7, 2021
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More than 20 years after the discovery of the parkin gene linked to young-onset Parkinson's disease, researchers at The Ottawa Hospital and the University of Ottawa may have finally figured out how this mysterious gene protects ...
Apr 7, 2021
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The Parkin gene protects nerve cells against functional impairment and cell death. It particularly ensures that mitochondria, cell organelles that are responsible for energy production, remain intact and that damaged mitochondria ...
Feb 5, 2020
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Researchers at Tokyo Metropolitan Institute of Medical Sciences are reporting new insight into how the Parkinson's disease-associated protein Parkin selects its targets. Cells depend on Parkin to help get rid of damaged mitochondria. ...
May 20, 2019
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Scientists at the University of Dundee have confirmed that a key cellular pathway that protects the brain from damage is disrupted in Parkinson's patients, raising the possibility of new treatments for the disease.
Nov 7, 2018
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A new study, published today in Nature Structural and Molecular Biology, moves researchers closer to understanding one of the crucial proteins involved in Parkinson's disease.
Jul 4, 2018
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Rapamycin, an FDA-approved drug that extends lifespan in several species, prevented Parkinson's disease (PD) in middle-age mice that were genetically fated to develop the incurable neurodegenerative motor disease that affects ...
Sep 16, 2015
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