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Scientists report first step in strategy for cell replacement therapy in Parkinson's disease

Induced pluripotent stem cells (iPSC) are a promising avenue for cell replacement therapy in neurologic diseases. For example, mouse and human iPSCs have been used to generate dopaminergic (DA) neurons that improve symptoms ...

Medical research created Jan 24, 2012 | popularity not rated yet | comments 0

New research reveals how alpha-synuclein interacts with cell membranes in Parkinson's disease

The accumulation of α-synuclein, a small, negatively charged protein, in neural cells, is one of the hallmarks of Parkinson's disease. It has been suggested that oligomeric α-synuclein causes membranes to become ...

Diseases, Conditions, Syndromes created Jan 18, 2012 | popularity not rated yet | comments 0 | with audio podcast

Researchers identify path to treat Parkinson's disease at its inception

(Medical Xpress) -- Imagine if doctors could spot Parkinson’s disease at its inception and treat the protein that triggers it before the disease can sicken the patient.   A team of researchers led by Basi ...

Medical research created Jan 16, 2012 | popularity 4.6 / 5 (7) | comments 0 | with audio podcast

Parkin larvae bring researchers closer to solving Parkinson's disease puzzle

(Medical Xpress) -- Scientists at the University of York have made a significant step forward in isolating the cause of Parkinson’s disease in younger adults.

Neuroscience created Jan 16, 2012 | popularity not rated yet | comments 0 | with audio podcast

Parkinson's treatment shows positive results in clinical testing

Researchers from the University of Florida and 14 additional medical centers reported results today in the online version of The Lancet Neurology journal indicating that deep brain stimulation — also known as DBS &# ...

Neuroscience created Jan 11, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

New study supports view that Lewy bodies are not the primary cause of cell death in Parkinson's Disease

The pathology of Parkinson's disease is characterized by a loss of dopamine-producing neurons in the pars compacta of the substantia nigra (SN), an area of the brain associated with motor control, along with the development ...

Medical research created Jan 09, 2012 | popularity not rated yet | comments 0 | with audio podcast

Demographic, clinical factors appear associated with survival in patients with Parkinson's disease

Demographics and clinical factors appear to be associated with survival in patients with Parkinson disease (PD), and the presence of dementia is associated with a significant increase in mortality, according to a report in ...

Parkinson's & Movement disorders created Jan 02, 2012 | popularity not rated yet | comments 0

UCF patented on induced pluripotent stem cells, iPS cells

A process that prompts a single gene to generate millions of supercharged stem cells, which can then turn into any kind of cell a body needs to repair itself, has been patented at the University of Central ...

Medical research created Dec 22, 2011 | popularity 5 / 5 (1) | comments 0

Scientists identify a novel therapy with potential for treating Parkinson's disease

Scientists at the University of Cambridge have made a significant step in the development of a novel therapy that could one day help to slow down, or even halt, the damage caused by Parkinson’s disease ...

Medical research created Dec 22, 2011 | popularity 5 / 5 (2) | comments 1 | with audio podcast

New findings about the prion protein and its interaction with the immune system

(Medical Xpress) -- Scrapie is a neurodegenerative disease which can function as a model for other diseases caused by an accumulation of proteins resulting in tissue malformations (proteinpathies), such as ...

Immunology created Dec 21, 2011 | popularity 5 / 5 (1) | comments 0

Innovative new strategy to treat Parkinson's disease

Stabilizing the cell's power-generating center protects against Parkinson's disease (PD) in a rat model, according to a report published online this week in the Journal of Experimental Medicine.

Medical research created Dec 19, 2011 | popularity not rated yet | comments 0

Genetic factors can predict the progression of Parkinson's disease

Parkinson's disease is marked by the abnormal accumulation of α-synuclein and the early loss of dopamine neurons in the substantia nigra region of the brain. A polymorphism in the promotor of α-synuclein gene known ...

Parkinson's & Movement disorders created Dec 16, 2011 | popularity 5 / 5 (1) | comments 0

Reprogramming brain cells important first step for new Parkinson's therapy, study finds

(Medical Xpress) -- In efforts to find new treatments for Parkinson’s Disease (PD), researchers from the Perelman School of Medicine at the University of Pennsylvania have directly reprogrammed astrocytes, ...

Medical research created Dec 13, 2011 | popularity 4.7 / 5 (3) | comments 0 | with audio podcast

Increased arm swing asymmetry is early sign of Parkinson's disease

People with Parkinson's disease swing their arms asymmetrically -- one arm swings less than the other -- when walking. This unusual movement is easily detected early when drugs and other interventions may help slow the disease, ...

Diseases, Conditions, Syndromes created Dec 13, 2011 | popularity not rated yet | comments 0 | with audio podcast

Test for Alzheimer's disease predicts cognitive decline in Parkinson's disease

A method of classifying brain atrophy patterns in Alzheimer's disease patients using MRIs can also detect cognitive decline in Parkinson's disease, according to a new study by researchers from the Perelman School of Medicine ...

Parkinson's & Movement disorders created Dec 12, 2011 | popularity not rated yet | comments 0 | with audio podcast