Oncology & Cancer

New role for an old protein: Cancer causer

A protein known to play a role in transporting the molecular contents of normal cells into and out of various intracellular compartments can also turn such cells cancerous by stimulating a key growth-control pathway.

Diseases, Conditions, Syndromes

Benefits of exercise may vary greatly in primary mitochondrial disease

Mitochondria serve as the main source of energy production in our cells, and endurance exercise is generally known to improve the function of mitochondria. However, the benefits of exercise in patients with primary mitochondrial ...

Immunology

A common metabolite may help treat autoimmune diseases

Researchers have revealed the modulatory effect of the anti-inflammatory metabolite itaconate on T helper and T regulatory cells, which may lead to new therapeutic approaches to treating some autoimmune diseases.

Immunology

Phosphorylation of Regnase-1 lets IL-17 run amok

When considering the role of the key immune molecule interleukin (IL)-17, the phrase "too much of a good thing" springs to mind. Because unlike some of its more sedate cytokine cousins which studiously direct the immune response ...

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