Using live but weakened malaria parasites as the basis of a vaccine represents a potentially encouraging anti-malaria strategy, according to results of follow-up animal studies performed after the conclusion of a recent clinical ...
Sep 8, 2011
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Through investigating the causes of brain swelling in cerebral malaria—a devastating parasitic disease that is fatal for one in five children—scientists have found a potential new treatment approach that could be safely ...
Jun 25, 2020
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Researchers in Japan have discovered that the Plasmodium parasites responsible for malaria rely on a human liver cell protein for their development into a form capable of infecting red blood cells and causing disease. The ...
Jun 12, 2019
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Groundbreaking studies published today in the New England Journal of Medicine and PLOS Medicine have found large numbers of malaria parasites hiding in the human spleen where they actively multiply in a previously unrecognized ...
May 27, 2021
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Immunological signatures can predict whether malaria-infected children will develop fever or other symptoms, suggests a study publishing September 3 in the journal Immunity. Surprisingly, activation of the well-known tumor-suppressor ...
Sep 3, 2019
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Pyramax, a fixed-dose combination of pyronaridine and artesunate, becomes the first antimalarial to be granted a positive scientific opinion from the European Medicines Agency (EMA) under Article 58. This once daily, 3-day ...
Feb 21, 2012
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The drug artemisinin is the world's most important first-line drug for the treatment of malaria, a disease spread by mosquitoes that was responsible for 627,000 deaths globally in 2020. To prevent the malaria parasite (Plasmodium ...
Aug 29, 2022
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A protein that plays a critical role in helping malaria parasites infect red blood cells—known as apical membrane protein 1 (AMA1)—has been found to bind to more than one receptor on the surface of the cells.
Mar 3, 2023
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A study of almost 3,800 pregnancies has provided the most accurate and direct evidence to date that malaria infection reduces early foetal growth. Low birth weight is the most important risk factor for neonatal mortality ...
Feb 9, 2012
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Drug resistance to the critical antimalarial therapeutics of the artemisinin family has emerged in Southeast Asia, highlighting the need to understand how these drugs work and how they can be used more effectively. Research ...
Apr 22, 2015
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