Diseases, Conditions, Syndromes

3D organoid models show brain mechanisms of Tourette syndrome

Tourette syndrome (TS) is a common disorder characterized by uncontrollable motor or vocal tics that manifests in childhood and can interfere with school performance, relationships, and quality of life. Using stem cells from ...

Medical research

Study illuminates sugar's role in common kidney disease

A study of kidney organoids in a novel lab environment might have downstream implications for the treatment of polycystic kidney disease (PKD), an incurable condition that affects more than 12 million people worldwide.

Neuroscience

Born to survive—How human neurons manage to live a century

Essentially all human tissues and organs have the capacity to heal, to renew cells which are damaged or killed. In this context, the human brain behaves fundamentally differently. The vast majority of nerve cells are created ...

Cardiology

Study finds two protein pathways downregulated in postnatal heart

In work published today in Stem Cell Reports, researchers from the University of Minnesota Medical School discovered two signaling pathways that are downregulated in human hearts after birth. These pathways, mitogen-activated ...

Medical research

How microglia contribute to Alzheimer's disease

One of the hallmarks of Alzheimer's disease is a reduction in the firing of some neurons in the brain, which contributes to the cognitive decline that patients experience. A new study from MIT shows how a type of cells called ...

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