Genetics

What role do genome variations play in tuberculosis?

Tuberculosis is caused by Mycobacterium tuberculosis. In 2016, this was the most common causative pathogen for death by infectious diseases. Therefore, investigating the biology of infection and disease development is important ...

Diseases, Conditions, Syndromes

Genetic variation impacts pharmacokinetics of exemestane

(HealthDay)—The OATP1B1 c.521>C single nucleotide polymorphism (SNP) influences exemestane pharmacokinetics in healthy postmenopausal women, according to a study published online July 29 in the Journal of Clinical Pharmacy ...

Genetics

Polymorphism in rs4343 of ACE gene linked to migraine

(HealthDay)—Angiotensin I-converting enzyme (ACE) gene rs4343 polymorphism is associated with the risk of migraine, according to a letter to the editor published online June 18 in CNS Neuroscience & Therapeutics.

Cardiology

MTHFR A1298C polymorphism not linked to MTX outcomes in RA

(HealthDay)—The methylene tetrahydrofolate reductase (MTHFR) gene A1298C polymorphism does not appear to be related to methotrexate (MTX) efficacy or toxicity in patients with rheumatoid arthritis (RA), according to a meta-analysis ...

Neuroscience

Method identifies epileptic patients who can benefit from surgery

Researchers affiliated with the University of Campinas (UNICAMP) in São Paulo State, Brazil, have shown that genetic information can be used to improve early prediction of the response to drugs in patients with mesial temporal ...

Genetics

Scientists developing protection mechanisms for genetic data

The more we know about our genome data, the better our doctors will be able to treat us in the future. But how can we make use of this sensitive data, without allowing it to be misused? The IT specialists around Stefan Katzenbeisser ...

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