Immunology

New insights into the control of inflammation

Scientists at The Wistar Institute discovered that Early Growth Response 1 (EGR1), a protein that turns on and off specific genes during blood cell development, inhibits expression of pro-inflammatory genes in macrophages. ...

Medical research

Discovery of aging mechanism for hematopoietic stem cells

By transferring mouse aged hematopoietic stem cells (aged HSCs) to the environment of young mice (bone marrow niche), it was demonstrated that the pattern of stem cell gene expression was rejuvenated to that of young hematopoietic ...

Neuroscience

Study reveals the unfolding of neuronal fate

In an interdisciplinary study combining developmental biology and computational biology, researchers from Karolinska Institutet and Medical University of Vienna (together with researchers in US, Italy and France), have revealed ...

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