To study the immune system in human health and disease, scientists commonly use the genetic manipulation of mouse hematopoietic stem and progenitor cells (HSPCs) as a powerful model system. These studies have been extremely ...
Jun 11, 2021
0
2
Bone marrow failure due to acute myeloid leukemia (AML) is a significant factor behind the disease's high rate of morbidity and mortality. Previous studies in mice suggest that AML cells inhibit healthy hematopoietic (blood) ...
May 20, 2021
0
2
Like many around the world, the lab of Professor Mriganka Sur in The Picower Institute for Learning and Memory at MIT has embraced the young technology of cerebral organoids, or 'minibrains,' for studying human brain development ...
May 11, 2021
0
21
Mitochondria play a key role in the formation of the lymphatic vasculature, according to a study published in Science Advances.
May 3, 2021
0
56
Neurons result from a highly complex and unique series of cell divisions. For example, in fruit flies, the process starts with stem cells that divide into mother cells (progenitor cells), that then divide into precursor cells ...
Apr 28, 2021
0
86
Leukemias are debilitating cancers of the hematopoietic or blood-forming cells of the bone marrow. Now, researchers at Tokyo Medical and Dental University (TMDU) describe an ingenious strategy against chronic myelomonocytic ...
Apr 16, 2021
0
19
Kidney development is a balancing act between the self-renewal of stem and progenitor cells to maintain and expand their numbers, and the differentiation of these cells into more specialized cell types. In a new study in ...
Apr 1, 2021
0
54
Researchers from the University of Science and Technology of China (USTC) of the Chinese Academy of Science (CAS), teamed up with scientists from Aix Marseille University, discovered that hematopoietic progenitors possessed ...
Mar 31, 2021
0
2
Prolonging a cellular defense response to inflammation could help regenerate the protective coating of axons that is degraded in diseases such as multiple sclerosis (MS), according to a Northwestern Medicine study published ...
Mar 30, 2021
0
14
Epithelial cell rests of Malassez derived from the periodontal ligament were transformed into progenitor stem-like cells by stimulation with epigenetic agents. Subsequently, the progenitor stem-like cells were directly differentiated ...
Mar 22, 2021
0
8
