Medical research

New mouse model provides unprecedented look at human immune system

Upon the prick of a finger or scrape of the knee, neutrophils rush to the scene. These white blood cells are the first line of defense against infection in all multicellular organisms. "They are absolutely essential for life," ...

Oncology & Cancer

Rhombic lip implicated in origins of high-risk medulloblastoma

Scientists at St. Jude Children's Research Hospital have discovered which cells give rise to certain high-risk groups of medulloblastoma. The findings will help researchers better understand the biology of the disease, as ...

Genetics

Researchers find that RNA exosome is key for B cell development

New research from UT Southwestern suggests that RNA exosomes—the cellular machines that degrade old molecules of RNA—play a key role in the development of B cells, which are critical to the immune system's ability to ...

Immunology

How one inflammatory disorder exacerbates another

The immune system remembers. Often this memory, primed by past encounters with threats like bacteria or viruses, is an asset. But when that memory is sparked by internal drivers, like chronic inflammation, it can prove detrimental, ...

Neuroscience

New discoveries about the origin of the brain's immune system

What gets into the brain and what doesn't is strictly regulated. Researchers at the Faculty of Medicine at the University of Freiburg have now studied phagocytes that coat the blood vessels in the brain and reinforce the ...

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