Medical research

Discovery of aging mechanism for hematopoietic stem cells

By transferring mouse aged hematopoietic stem cells (aged HSCs) to the environment of young mice (bone marrow niche), it was demonstrated that the pattern of stem cell gene expression was rejuvenated to that of young hematopoietic ...

Medical research

New method creates endless supply of kidney precursor cells

Salk Institute scientists have discovered the holy grail of endless youthfulness—at least when it comes to one type of human kidney precursor cell. Previous attempts to maintain cultures of the so-called nephron progenitor ...

Medical research

Helping blood cells regenerate after radiation therapy

Patients with blood cancers such as leukemia and lymphoma are often treated by irradiating their bone marrow to destroy the diseased cells. After the treatment, patients are vulnerable to infection and fatigue until new blood ...

Neuroscience

In building the brain, cell pedigree matters

The cerebral cortex—the brain's epicenter of high-level cognitive functions, such as memory formation, attention, thought, language and consciousness—has fascinated neuroscientists for centuries.

Medical research

New strategy to treat multiple sclerosis shows promise in mice

Scientists at The Scripps Research Institute (TSRI) have identified a set of compounds that may be used to treat multiple sclerosis (MS) in a new way. Unlike existing MS therapies that suppress the immune system, the compounds ...

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