In a healthy brain, the multistep waste clearance process known as autophagy routinely removes and degrades damaged cell components—including malformed proteins like tau and toxic mitochondria. This cellular debris would ...
Oct 12, 2020
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A new, rare genetic form of dementia has been discovered by a team of Penn Medicine researchers. This discovery also sheds light on a new pathway that leads to protein build up in the brain—which causes this newly discovered ...
Oct 2, 2020
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Accumulation of assembled tau protein in the central nervous system is characteristic of Alzheimer's disease and several other neurodegenerative diseases, called tauopathies. Recent studies have revealed that propagation ...
Sep 23, 2020
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A genetic variation in some people may be associated with cognitive decline that can't be explained by deposits of two key proteins associated with Alzheimer's disease, amyloid β and tau, according to a study published in ...
Sep 16, 2020
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Researchers at the University of Alabama at Birmingham are on the track of a gene that might play a role in the development of Alzheimer's disease. The research team is studying a gene called BIN1, which was first linked ...
Sep 4, 2020
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Dozens of molecules may tangle up with rogue bundles of tau, a protein that normally gives nerve fibers structure, to cause brain cell damage that contributes to neurodegenerative diseases, a new study shows.
Jul 28, 2020
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Super-agers, or individuals whose cognitive skills are above the norm even at an advanced age, have been found to have increased resistance to tau and amyloid proteins, according to research presented at the Society of Nuclear ...
Jul 15, 2020
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Researchers at Karolinska Institutet have imaged tau protein in the brains of living patients with Alzheimer's disease. The amount and spread of tau proved a predictor of future memory loss. Brain imaging for measuring tau ...
Jul 3, 2020
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Neurons that regularly remodel are more prone to Alzheimer's disease and die when that remodeling goes awry, a new study suggests. The work is the first to track the progression of Alzheimer's at the genetic and molecular ...
Jun 29, 2020
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A new blood test for Alzheimer's disease has been developed under the leadership of researchers at the University of Gothenburg. The method is based on measuring a specific variant of tau protein in ordinary blood samples, ...
Apr 23, 2020
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