Medical research

Mitochondrial mutations and disease

Mitochondria are cellular organelles with their own DNA. Their role in power generation makes them susceptible to oxidative damage, including the formation of DNA-damaging chemical complexes called adducts.

Oncology & Cancer

Block estrogen to treat lung disease

The strongest epidemiological risk factor for many forms of pulmonary arterial hypertension (PAH) is female gender. Increased estrogen makes females three times more likely to develop PAH, a chronic disease that eventually ...

Cardiology

Breathing in a new gene therapy to treat pulmonary hypertension

Mount Sinai has partnered with Theragene Pharmaceuticals, Inc. to advance a novel airway-delivered gene therapy for treating pulmonary hypertension (PH), a form of high blood pressure in blood vessels in the lungs that is ...

Cardiology

MRI measures can predict pulmonary arterial HTN outcome

(HealthDay)—Magnetic resonance imaging (MRI) measures can predict outcomes in pulmonary arterial hypertension (PAH), according to a study published online March 22 in the American Journal of Respiratory and Critical Care ...

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