News tagged with receptors

Related topics: cells · protein · brain · molecules · nerve cells

New model of T cell activation

T cell receptors are an important part of the human immune system. They are able to switch their conformation from an inactive to an active state spontaneously without any antigens present. Cholesterol binds and stabilizes ...

20 hours ago
popularity3 comments 0

Fighting addiction through the gut-brain axis

"We are what we eat." This piece of folk knowledge is true in more ways than one. In fact, it is well known that food, through action on the enteric system, has direct effects on the brain. The mechanisms underlying this ...

May 25, 2016
popularity26 comments 0

Receptor (biochemistry)

In biochemistry, a receptor is a protein molecule, embedded in either the plasma membrane or cytoplasm of a cell, to which a mobile signaling (or "signal") molecule may attach. A molecule which binds to a receptor is called a "ligand," and may be a peptide (such as a neurotransmitter), a hormone, a pharmaceutical drug, or a toxin, and when such binding occurs, the receptor undergoes a conformational change which ordinarily initiates a cellular response. However, some ligands merely block receptors without inducing any response (e.g. antagonists). Ligand-induced changes in receptors result in physiological changes which constitute the biological activity of the ligands.

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