Diseases, Conditions, Syndromes

T-cell abnormalities in severe COVID-19 cases

There is an idea within the coronavirus research field that there is some kind of T-cell abnormality in critically ill COVID-19 patients, but specific details have not yet been clarified. To shed light on the problem, a research ...

Medical research

New insights into a potential target for autoimmune disease

Immune response is a balancing act: Too much can lead to inflammatory or autoimmune disease; too little could lead to a serious infection. Regulatory T cells, or Tregs, are important players in striking this balance, acting ...

Oncology & Cancer

Cancer immunotherapy 'uniquely suppressed' by liver tumors

Though cancer immunotherapy has become a promising standard-of-care treatment—and in some cases, perhaps a cure—for a wide variety of different cancers, it doesn't work for everyone, and researchers have increasingly ...

Genetics

Scientists map genes controlling immune system 'brakes'

Unlike most T cells, which launch immune responses against foreign molecules, regulatory T cells are the peacekeepers of the human immune system, damping down inflammatory reactions when they're not needed. Now, researchers ...

Cardiology

T cells can shift from helping to harming in atherosclerosis

High cholesterol kills. In fact, one in four Americans will die from the consequences of atherosclerosis, the buildup of plaques of fat and cholesterol in the arteries. Statins have helped reduce mortality, but millions are ...

Oncology & Cancer

Researchers find dual inhibitor may be safer for CLL patients

Chronic lymphocytic leukemia (CLL) is the most common leukemia in adults. One in four new leukemia cases are CLL. Early-stage CLL patients often do not require therapy, but for those with aggressive disease or who have failed ...

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