Genetics

Scientists map genes controlling immune system 'brakes'

Unlike most T cells, which launch immune responses against foreign molecules, regulatory T cells are the peacekeepers of the human immune system, damping down inflammatory reactions when they're not needed. Now, researchers ...

Medical research

Engineered T cells for type 1 diabetes move closer to clinic

For much of the last decade, Dr. David Rawlings, director of Seattle Children's Research Institute's Center for Immunity and Immunotherapies, has dreamed of developing a therapy for children with type 1 diabetes that doesn't ...

Medical research

Study reveals bile metabolite of gut microbes boosts immune cells

A Ludwig Cancer Research study has discovered a novel means by which bacterial colonies in the small intestine support the generation of regulatory T cells—immune cells that suppress autoimmune reactions and inflammation. ...

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