Oncology & Cancer

Culprit found in breast cancer resistance to tamoxifen

Researchers have discovered that a protein found naturally in cells that provides some protection from viruses is responsible for creating mutations that drive resistance to tamoxifen treatment in breast cancer. Because the ...

Diabetes

Enzyme insight could lead to new diabetes treatment

Research led by the Centenary Institute has discovered that the lack of an enzyme in the liver called sphingosine kinase 2 (SphK2) results in pronounced insulin resistance and glucose intolerance, both symptoms of early stage ...

Diabetes

Insulin-sensitive fat leads to obesity

SORLA is a protein that influences the balance of metabolic processes in adipose tissue, a particular form of fat. Too much of it makes fat cells overly sensitive to insulin, which leads them to break down less fat. SORLA ...

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