Genetics

Gene therapy targets inner retina to combat blindness

Gene therapy to the inner retina prevented blindness in a mouse model of the neuro-degenerative disorder CLN3 Batten disease. Adeno-associated viral (AAV)-mediated expression of the human CLN3 gene led to significant survival ...

Ophthalmology

Scientists discover gene tied to profound vision loss

An exhaustive hereditary analysis of a large Louisiana family with vision issues has uncovered a new gene tied to an incurable eye disorder called retinitis pigmentosa, according to an examination led by scientists at The ...

Neuroscience

Breakthrough in the fight against blindness

A team of researchers at the IRCM led by Michel Cayouette, PhD, identified one of the genes responsible for producing a type of cell required for vision. The breakthrough, published in the scientific journal Neuron, could ...

Ophthalmology

Loss of pericytes deteriorates retinal environment

Inside the eye, at the interface between blood vessels and the retina, lies a boundary that prevents harmful substances present in the blood from entering the retina. Researchers at the Center for Vascular Research, within ...

Medical research

Caring for blindness: A new protein in sight?

Vasoproliferative ocular diseases are responsible for sight loss in millions of people in the industrialised countries. Many patients do not currently respond to the treatment offered, which targets a specific factor, VEGF. ...

Ophthalmology

Bionic eye helps UK pensioner see in world first

A partially sighted British pensioner has had most of his vision restored thanks to a "bionic eye"—a device that converts video images from a miniature camera installed in his glasses to his brain.

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