Oncology & Cancer
Disabling cancer cells' defenses against radiation
Researchers at Winship Cancer Institute are developing a technique to remove cancer cells' defenses against radiation.
Mar 15, 2012
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News tagged with rna interference
Medical research
Delivering RNA with tiny sponge-like spheres
For the past decade, scientists have been pursuing cancer treatments based on RNA interference — a phenomenon that offers a way to shut off malfunctioning genes with short snippets of RNA. However, one huge challenge ...
Feb 27, 2012
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Genetics
Team perfects non-lethal way of switching off essential genes in mice
One way of discovering a gene's function is to switch it off and observe how the loss of its activity affects an organism. If a gene is essential for survival, however, then switching it off permanently will kill the organism ...
Apr 14, 2011
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Cardiology
Patisiran can preserve functional capacity in transthyretin amyloidosis, according to study
For patients with transthyretin amyloidosis (ATTR amyloidosis), administration of an RNA interference therapeutic agent, patisiran, over 12 months results in preserved functional capacity, according to a study published in ...
Oct 27, 2023
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Oncology & Cancer
An ancient anti-cancer mechanism: DISE
A new editorial paper titled "DISE, an ancient anti-cancer mechanism that senses mutational load in cancerous cells?" has been published in Oncotarget.
Oct 3, 2023
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Medications
Clinical trial finds novel therapy markedly reduces lipoprotein(a) levels in people with cardiovascular disease
Lipoprotein(a) is a special type of bad cholesterol that is believed to contribute to heart disease, but there are no approved pharmacological therapies to decrease its concentration in the bloodstream. Olpasiran is an investigational ...
Nov 7, 2022
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Medical research
Measuring levels of proteins in eye fluid may accurately predict need for lifelong macular degeneration therapy
In a study of eye fluid from 38 patients, Johns Hopkins Medicine researchers say they have found that levels of a specific protein appears to help accurately predict whether people with the wet form of age-related macular ...
Jun 29, 2022
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Oncology & Cancer
New insights into Glioblastoma invasiveness
One of the hallmarks of Glioblastoma (GBM), the most aggressive type of brain cancer, is its high invasive capacity, which leads to its expansion into normal brain tissue. GBM cells insinuate themselves in the interstitial ...
Dec 11, 2020
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Medications
Treatments for coronavirus: Repurposing existing drugs
Why develop new drugs to combat the replication of the coronavirus if existing approved substances could do the same thing? Repurposing drugs in this fashion could offer a faster remedy against pathogens that have as yet ...
Apr 10, 2020
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Medications
Promising results for new acute porphyria treatment
Acute porphyria is a group of uncommon diseases that can cause severe, potentially life-threatening attacks of abdominal pain, nausea, vomiting and paralysis. Liver transplantation is currently the only effective treatment ...
Feb 7, 2019
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