The origin of certain cancers in the sarcoma group is associated with a hitherto unknown interaction among different proteins. Findings now being presented create the opportunity to test new treatments of these forms of sarcoma.
Apr 9, 2019
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95
Researchers from Ludwig-Maximilians-Universitaet (LMU) in Munich have elucidated at the molecular level how an otherwise innocuous inherited mutation that is quite common in European populations interacts with a spontaneous ...
Jul 28, 2015
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82
When sarcomas become large enough and outgrow their blood supply, they become vulnerable to hypoxia—a lack of oxygen. That adaptation not only enables them to survive the stress of low oxygen—it also enables them to withstand ...
May 12, 2015
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5
A team of WA researchers has uncovered new genes that could play an important role in the development of sarcoma, a group of rare bone, muscle and connective tissue cancers.
Jun 11, 2019
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14
A virus linked to cancer can hijack the host's cellular mail and could help drive changes in the environment around tumors, researchers from the University of North Carolina Lineberger Comprehensive Cancer Center found.
Feb 22, 2019
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8
A University of Colorado Cancer Center study published in the journal PLoS One finds alterations in expression of genes PIK3R3 and PTEN, more commonly observed in adult tumors, in the rare, young-adult bone cancer Ewing Sarcoma, ...
Feb 3, 2015
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15
A combination of chemotherapy and chimeric antigen receptor (CAR) T cells designed to target the protein HER2 was found to be safe and showed clinical responses in pediatric and adult patients with advanced HER2-positive ...
Mar 31, 2019
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4
A pair of targeted therapies shrank tumors in some patients with treatment-resistant Ewing's sarcoma or desmoplastic small-round-cell tumors, according to research led by investigators from The University of Texas MD Anderson ...
Apr 1, 2012
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0
In the current issue of Proceedings of the National Academy of Sciences, researchers from Nationwide Children's Hospital describe a new paradigm for treating transcription factor-driven cancers. The study focuses on Ewing ...
Sep 18, 2017
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87
Scientists at Cold Spring Harbor Laboratory (CSHL) have discovered a new drug target for Ewing sarcoma, a rare kind of cancer usually diagnosed in children and young adults. Their experiments show that the cells causing this ...
Jan 19, 2023
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