News tagged with side effects

Related topics: drug , patients , food and drug administration , cancer , clinical trials

Genetic testing beneficial in melanoma treatment

(Medical Xpress)—Genetic screening of cancer can help doctors customize treatments so that patients with melanoma have the best chance of beating it, according to the results of a clinical trial by researchers at the University ...

Apr 04, 2014
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Common cold meds may pose health threats

(HealthDay)—Over-the-counter sinus and pain remedies that combine two common ingredients—phenylephrine and acetaminophen—might cause serious side effects such as high blood pressure, dizziness and tremors, ...

Mar 19, 2014
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Chemo-free treatment a possibility for leukemia / lymphoma

Patients with terminal forms of leukaemia and lymphoma who have run out of treatment options could soon benefit from a new drug, which not only puts an end to chemotherapy and has virtually no side effects but also improves ...

Mar 19, 2014
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Experimental drug helps body fight advanced melanoma

(HealthDay)—An experimental drug that harnesses the power of the body's immune system to fight cancer has helped some patients with advanced melanoma keep their disease in check for several years, a new ...

Mar 03, 2014
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Adverse effect

In medicine, an adverse effect is a harmful and undesired effect resulting from a medication or other intervention such as surgery. An adverse effect may be termed a "side effect", when judged to be secondary to a main or therapeutic effect, and may result from an unsuitable or incorrect dosage or procedure, which could be due to medical error. Adverse effects are sometimes referred to as "iatrogenic" because they are generated by a physician/treatment. Some adverse effects only occur only when starting, increasing or discontinuing a treatment. Using a drug or other medical intervention which is contraindicated may increase the risk of adverse effects. Adverse effects may cause medical complications of a disease or procedure and negatively affect its prognosis. They may also lead to non-compliance with a treatment regimen.

The harmful outcome is usually indicated by some result such as morbidity, mortality, alteration in body weight, levels of enzymes, loss of function, or as a pathological change detected at the microscopic, macroscopic or physiological level. It may also be indicated by symptoms reported by a patient. Adverse effects may cause a reversible or irreversible change, including an increase or decrease in the susceptibility of the individual to other chemicals, foods, or procedures, such as drug interactions.

In clinical trials, a distinction is made between adverse events (AEs) and serious adverse events (SAEs). Generally, any event which causes death, permanent damage, birth defects, or requires hospitalization is considered an SAE. The results of these trials are often included in the labeling of the medication to provide information both for patients and the prescribing physicians.

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