News tagged with simvastatin


Cholesterol-lowering drug may reduce exercise benefits for obese adults, study finds

Statins, the most widely prescribed drugs worldwide, are often suggested to lower cholesterol and prevent heart disease in individuals with obesity, diabetes and metabolic syndrome, which is a combination of medical disorders ...

Cardiology created May 15, 2013 | popularity not rated yet | comments 0

High potency statins pose significantly higher risk of kidney injury than low potency, say experts

Patients taking high potency statins for high blood pressure are at a 34% higher risk of being hospitalised for acute kidney injury (AKI), compared with those taking low potency statins, a paper published today in BMJ sugges ...

Cardiology created Mar 19, 2013 | popularity 5 / 5 (1) | comments 1

Study finds statin costs 400 percent higher in US compared to UK

In the United States, the cost paid for statins (drugs to lower cholesterol) in people under the age of 65 who have private insurance is approximately 400 percent higher than comparable costs paid by the government in the ...

Medications created Jan 05, 2012 | popularity 3.7 / 5 (3) | comments 12

HPS2-THRIVE trial: Side-effects cause a quarter of heart patients to stop treatment

The largest randomised study of the vitamin niacin in patients with occlusive arterial disease (narrowing of the arteries) has shown a significant increase in adverse side-effects when it is combined with statin treatment.

Cardiology created Feb 26, 2013 | popularity not rated yet | comments 0

Statins may help prevent irregular heartbeat in elderly

(HealthDay) -- The widely used class of cholesterol-lowering medications known as statins may help elderly patients with high blood pressure avoid developing atrial fibrillation, a heart rhythm abnormality ...

Cardiology created May 10, 2012 | popularity not rated yet | comments 0 | with audio podcast

Statins shown to cause fatigue

In a study of more than 1,000 adults, researchers at the University of California, San Diego, found that individuals taking cholesterol-lowering statin drugs are more likely than non-users to experience decreased energy, ...

Medications created Jun 11, 2012 | popularity not rated yet | comments 0 | with audio podcast

Cholesterol drug shows benefit in animal study of Alzheimer's disease

A cholesterol drug commonly prescribed to reduce cardiovascular disease risk restores blood vessel function in a mouse model of Alzheimer's disease, according to a study in the April 4 issue of The Journal of Neuroscience. The dr ...

Alzheimer's disease & dementia created Apr 03, 2012 | popularity 5 / 5 (1) | comments 0

ICD-9 codes underestimate statin-linked rhabdomyolysis

(HealthDay) -- Use of diagnostic codes, such as International Classification of Diseases -- Ninth Revision (ICD-9) codes, may result in misclassification of rare, adverse drug reactions (ADRs), including the ...

Medications created Apr 18, 2012 | popularity not rated yet | comments 0

Fenofibrate / simvastatin benefit in dyslipidemia explored

(HealthDay)—Combination treatment with fenofibrate and simvastatin (FENO-S) significantly reduces postprandial (PP) triglyceride (TG) levels compared with simvastatin alone in all subjects, regardless of ...

Diabetes created Nov 01, 2012 | popularity 4.5 / 5 (2) | comments 0

Gut bacteria may affect whether a statin drug lowers cholesterol

Statins can be effective at lowering cholesterol, but they have a perplexing tendency to work for some people and not others. Gut bacteria may be the reason.

Medical research created Oct 13, 2011 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Statins plus exercise best at lowering cholesterol, study finds

(HealthDay)—People who exercise along with taking statins to lower their high cholesterol levels can dramatically reduce their risk of dying, a large new study suggests.

Cardiology created Nov 28, 2012 | popularity not rated yet | comments 1 | with audio podcast

Extended-Release niacin raises fasting glucose levels

(HealthDay) -- The combination of extended-release niacin (N) with ezetimibe plus simvastatin (E/S) to treat hyperlipidemia is associated with increased fasting glucose (FG) levels compared with E/S alone, ...

Diabetes created Mar 28, 2012 | popularity not rated yet | comments 0

Heart disease: Long-term study proves benefit of statins

Statins safely reduce the risk of cardiovascular illness even years after treatment is stopped, according to a probe into the popular cholesterol-busters published on Wednesday.

Cardiology created Nov 23, 2011 | popularity 5 / 5 (1) | comments 11

Niacin added to statin therapy increases HDL cholesterol levels but does not improve HDL functionality, research shows

While two large clinical trials recently showed that adding niacin to statin therapy failed to improve clinical outcomes despite a significant increase in HDL-C levels, little is known about exactly why the increased HDL-C ...

Cardiology created Mar 12, 2013 | popularity 5 / 5 (1) | comments 0

Topical simvastatin shown to accelerate wound healing in diabetes

Delayed wound healing is a major complication of diabetes because the physiological changes in tissues and cells impair the wound healing process. This can result in additional disease outcomes such as diabetic foot ulcer, ...

Diabetes created Nov 27, 2012 | popularity not rated yet | comments 0