News tagged with single nucleotide polymorphisms
Gene mutation as cause of breast and ovarian cancer
A change to the so-called TERT gene considerably increases the risk of breast and ovarian cancer. This is the result of a current, multicenter study in which the University Department of Gynaecology and the ...
Cancer
May 10, 2013 |
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With two new methods, scientists hope to improve genome-wide association studies
As scientists probe and parse the genetic bases of what makes a human a human (or one human different from another), and vigorously push for greater use of whole genome sequencing, they find themselves increasingly ...
Genetics
Apr 26, 2013 |
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Sequencing tracks animal-to-human transmission of bacterial pathogens
Researchers have used whole genome sequencing to reveal if drug-resistant bacteria are transmitted from animals to humans in two disease outbreaks that occurred on different farms in Denmark. The results, which are published ...
Genetics
Mar 25, 2013 |
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Genetic variation doubles risk of aortic valve calcification
Researchers have found a genetic variant that doubles the likelihood that people will have calcium deposits on their aortic valve. Such calcification, if it becomes severe, can cause narrowing or a blockage of the aortic ...
Cardiology
Feb 06, 2013 |
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More links found between schizophrenia, cardiovascular disease
A new study, to be published in the Feb. 7, 2013 issue of the American Journal of Human Genetics, expands and deepens the biological and genetic links between cardiovascular disease and schizophrenia. Cardiovascular diseas ...
Genetics
Jan 31, 2013 |
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1,092 genomes and counting
Focusing on fine features in order to see "the big picture" seems almost counterintuitive, but that is exactly what is happening in the field of genomics. Researchers are sequencing human genomes, cataloging ...
Genetics
Nov 16, 2012 |
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Smoking and hyperactivity share common genetic risk factor
A variation of a particular gene may link the behaviours typical of childhood attention hyperactivity disorder, or ADHD for short, and those associated with smoking, suggests research published online in the Archives of Di ...
Attention deficit disorders
Oct 30, 2012 |
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Researchers find genetic predictors of fatigue for some prostate cancer patients
Researchers at Moffitt Cancer Center and the University of South Florida have found that men with prostate cancer who receive androgen deprivation therapy may predictably suffer from fatigue if they have single nucleotide ...
Cancer
Oct 26, 2012 |
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Genome-wide study identifies eight new susceptibility loci for atopic dermatitis
Japanese researchers at the RIKEN Center for Genomic Medicine (CGM) and their colleagues have identified 8 new loci associated with susceptibility to atopic dermatitis in the Japanese population. The findings, ...
Genetics
Oct 07, 2012 |
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New light on genetics of autism
The genetics of autism is complex and possibly influenced by mutations with very large effects. EU genomics research has found more candidate genes that increase susceptibility to the condition.
Autism spectrum disorders
Sep 14, 2012 |
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Genetic counseling doesn't affect pre-diabetes behavior
(HealthDay)—Receiving genetic risk counseling does not significantly alter self-reported motivation or prevention program adherence for overweight individuals at risk for type 2 diabetes, according to a ...
Diabetes
Sep 07, 2012 |
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New study discovers genomic variant that increases risk of some brain tumors
People who carry a "G" instead of an "A" at a specific spot in the sequence of their genetic code have roughly a six-fold higher risk of developing certain types of brain tumors, according to a study by researchers at the ...
Genetics
Aug 26, 2012 |
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Researchers create powerful new method to analyze genetic data
University of Texas Medical Branch at Galveston researchers have developed a powerful visual analytical approach to explore genetic data, enabling scientists to identify novel patterns of information that could be crucial ...
Genetics
Jun 12, 2012 |
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Large-scale study of East Asian individuals reveals a number of previously overlooked genetic variants
Broad, population-based investigations known as genome-wide association studies (GWAS) are now a standard tool for helping scientists to pinpoint genetic variations that can contribute to disease risk or pathology. ...
Genetics
Jan 27, 2012 |
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Study gauges emotional toll of direct-to-consumer genetic testing
Among the latest health care trends seeking to advance "individualized medicine" are private companies marketing genetic testing directly to patients. The mail-in kits, with price tags as high as $2,500, use a saliva specimen ...
Health
Oct 03, 2011 |
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Single-nucleotide polymorphism
A single-nucleotide polymorphism (SNP, pronounced snip) is a DNA sequence variation occurring when a single nucleotide — A, T, C, or G — in the genome (or other shared sequence) differs between members of a species (or between paired chromosomes in an individual). For example, two sequenced DNA fragments from different individuals, AAGCCTA to AAGCTTA, contain a difference in a single nucleotide. In this case we say that there are two alleles : C and T. Almost all common SNPs have only two alleles.
Within a population, SNPs can be assigned a minor allele frequency — the lowest allele frequency at a locus that is observed in a particular population. This is simply the lesser of the two allele frequencies for single-nucleotide polymorphisms[1]. There are variations between human populations, so a SNP allele that is common in one geographical or ethnic group may be much rarer in another.
For more information about Single-nucleotide polymorphism, read the full article at
Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
