Northwestern Medicine investigators led by Derek Walsh, Ph.D., professor of Microbiology-Immunology, have discovered how poxviruses disarm and evade mitochondrial-driven antiviral responses for their replication in host cells, ...
Dec 19, 2023
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Vaccines against smallpox given until the mid-1970s offer continuing cross-reactive immunity to mpox, researchers from Karolinska Institutet in Sweden report in a study published in Cell Host & Microbe.
May 23, 2023
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The mpox virus is closely related to the smallpox virus (variola virus), which caused large, deadly outbreaks before it was eradicated by vaccination at the end of the 1970s. While the smallpox virus led to very severe disease ...
Jan 6, 2023
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Pox viruses are able to get a head start on infecting a host by delivering a package of proteins that directly interferes with the body's innate immune system.
Jul 14, 2022
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The global eradication of smallpox in the 1980s was achieved by intradermal vaccination with vaccinia virus. A study published in PLOS Pathogens by Evgeniya V. Shmeleva, Brian J. Ferguson and Geoffrey L. Smith at University ...
Apr 21, 2022
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Scientists have discovered extinct strains of smallpox in the teeth of Viking skeletons—proving for the first time that the killer disease plagued humanity for at least 1400 years.
Jul 23, 2020
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New genetic research from an international team including McMaster University, University of Helsinki, Vilnius University and the University of Sydney, suggests that smallpox, a pathogen that caused millions of deaths worldwide, ...
Dec 8, 2016
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(Medical Xpress)—The question facing pathobiologist Paulo Verardi is not whether vaccines are effective in controlling disease – they are – it is how they can be made both highly safe and highly effective at the same ...
Sep 5, 2013
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A genetically-engineered virus tested in 30 terminally-ill liver cancer patients significantly prolonged their lives, killing tumours and inhibiting the growth of new ones, scientists reported on Sunday.
Feb 10, 2013
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Researchers from the Infection Biology Lab at the Department of Medicine and Life Sciences (MELIS) at Pompeu Fabra University and the HIV Unit at Hospital del Mar Research Institute have shown that intradermal vaccination ...
Jan 12, 2024
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