News tagged with stem cell transplantation
(Medical Xpress) -- Researchers from Japan recently published a paper in PLoS One describing their successful growth and transplantation of new teeth created from the stem cells of mice.
Medical research Jul 13, 2011 | 4.9 / 5 (23) | 8 |
Among the many hurdles to be cleared before human embryonic stem cells can achieve their therapeutic potential is determining whether or not transplanted cells can functionally integrate into target organs or tissues.
Neuroscience Nov 21, 2011 | 4.9 / 5 (10) | 0 |
Scientists at Duke University Medical Center have shown the ability to turn scar tissue that forms after a heart attack into heart muscle cells using a new process that eliminates the need for stem cell transplant.
Cardiology Apr 26, 2012 | 4.9 / 5 (10) | 2 |
A 36-year-old man who had tracheal cancer has received a new lab-made windpipe seeded with his own stem cells in a procedure in Sweden they call the first successful attempt of its kind, officials said Thursday.
Medical research Jul 07, 2011 | 5 / 5 (9) | 4
Treating patients with cells may one day become as common as it is now to treat the sick with drugs made from engineered proteins, antibodies or smaller chemicals, according to UC San Francisco researchers. They outlined ...
Medical research Apr 03, 2013 | 5 / 5 (8) | 0 |
(Medical Xpress) -- Two people in Scotland have received stem cell transplants into their eyes in a clinical trial that is aimed at restoring vision in people that suffer some degree of blindness due to damage ...
Ophthalmology May 22, 2012 | 4.6 / 5 (8) | 1 |
(Medical Xpress)—In a new study appearing this month in the Journal of Neuroscience, researchers have unlocked the complex cellular mechanics that instruct specific brain cells to continue to divide. This d ...
Neuroscience Nov 01, 2012 | 4.6 / 5 (7) | 0 |
Johns Hopkins researchers have demonstrated that human liver cells derived from adult cells coaxed into an embryonic state can engraft and begin regenerating liver tissue in mice with chronic liver damage.
Medical research May 11, 2011 | 4.3 / 5 (6) | 2 |
For decades scientists around the world have attempted to regenerate primary liver cells known as hepatocytes because of their numerous biomedical applications, including hepatitis research, drug metabolism and toxicity studies, ...
Medical research Feb 25, 2013 | 5 / 5 (5) | 0 |
Raising hopes for cell-based therapies, UC San Francisco researchers have created the first functioning human thymus tissue from embryonic stem cells in the laboratory. The researchers showed that, in mice, ...
Immunology May 16, 2013 | 4.8 / 5 (5) | 0 |
Some stem cells can lay dormant for more than two weeks in a dead person and then be revived to divide into new, functioning cells, scientists in France said Tuesday.
Medical research Jun 12, 2012 | 4.2 / 5 (5) | 3
For the first time, Massachusetts General Hospital (MGH) researchers have isolated egg-producing stem cells from the ovaries of reproductive age women and shown these cells can produce what appear to be normal egg cells or ...
Medical research Feb 26, 2012 | 5 / 5 (4) | 1 |
Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is untreatable and fatal. Nerve cells in the spinal cord die, eventually taking away a person's ability to move or even breathe. A ...
Medical research Dec 19, 2012 | 5 / 5 (4) | 0 |
A study by Columbia researchers suggests that cells in the patient's intestine could be coaxed into making insulin, circumventing the need for a stem cell transplant. Until now, stem cell transplants have been seen by many ...
Genetics Mar 11, 2012 | 4.8 / 5 (4) | 0 |
(Medical Xpress) -- Researchers in the Department of Pathology at Stony Brook University School of Medicine have discovered a laboratory method to expand adult hematopoietic stem cells (HSCs) using the SALL4 ...
Genetics Jun 07, 2011 | 4.3 / 5 (4) | 0 |
Hematopoietic stem cell transplantation
Hematopoietic stem cell transplantation (HSCT) is the transplantation of blood stem cells derived from the bone marrow (in this case known as bone marrow transplantation) or blood. Stem cell transplantation is a medical procedure in the fields of hematology and oncology, most often performed for people with diseases of the blood, bone marrow, or certain types of cancer.
With the availability of the stem cell growth factors GM-CSF and G-CSF, most hematopoietic stem cell transplantation procedures are now performed using stem cells collected from the peripheral blood, rather than from the bone marrow. Collecting peripheral blood stem cells provides a bigger graft, does not require that the donor be subjected to general anesthesia to collect the graft, results in a shorter time to engraftment, and may provide for a lower long-term relapse rate.
Hematopoietic stem cell transplantation remains a risky procedure with many possible complications; it has traditionally been reserved for patients with life-threatening diseases. While occasionally used experimentally in nonmalignant and nonhematologic indications such as severe disabling auto-immune disease and cardiovascular disease, the risk of fatal complications appears too high to gain wider acceptance.
For more information about Hematopoietic stem cell transplantation, read the full article at
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