Researchers at UNC Lineberger Comprehensive Cancer Center and colleagues have found that measuring activation of immune-system B cells may be better than measuring either T-cell activation or the total number of immune cells ...
Jan 5, 2023
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40
T cells aren't the first immune forces on the scene, they arrive after being alerted by other immune system warriors that a microbe has invaded or a cancer has silently seeded.
Immune checkpoint inhibitors have revolutionized cancer care. The therapy works by preventing tumors from shutting down the immune response, which in turn allows T cells to kill cancer cells. Established checkpoint inhibitors ...
Jun 27, 2022
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23
In a first-of-its-kind experiment, researchers have identified links between 127 genes and immune diseases, providing newfound insights into the sequence and timing of gene activity during the activation of T cells, a key ...
May 26, 2022
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54
A team led by Northwestern Medicine investigators has discovered differences in the distribution and interaction of T-cells within the microenvironment of different regions of both brain tumors and brain metastases, according ...
Apr 15, 2022
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59
Yale scientists have identified a way to "supercharge" tumor-attacking T cells, a finding that may not only improve the effectiveness of a promising type of cell-based cancer immunotherapy but also expand the number of cancers ...
Mar 10, 2022
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466
Blocking a protein chain reaction makes childhood leukemia cells more sensitive to an existing targeted treatment, a new study shows. The research is still at an early stage, but the drugs used in the study already exist, ...
Feb 25, 2022
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97
Lupus (systemic lupus erythematosus), an autoimmune disease in which the body recognizes and attacks its own tissues, can affect many organs, including the kidneys. About fifty percent of patients diagnosed with lupus develop ...
Jan 11, 2022
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15
New research from The University of Texas MD Anderson Cancer Center found that treatment with antihistamines, a commonly used allergy medication, was associated with improved responses to immune checkpoint inhibitors. The ...
Nov 24, 2021
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Armed with a novel strategy they developed for bolstering the body's immune response, scientists at Albert Einstein College of Medicine have successfully suppressed HIV infections in mice—offering a path to a functional ...
Oct 21, 2021
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