Immunology

Immune responses in chronic inflammatory bowel diseases

Chronic inflammatory bowel diseases (IBDs) like Crohn's disease and ulcerative colitis are characterized by inflammation of the gastrointestinal tract which flares up in phases and which is accompanied by abdominal pain, ...

Diseases, Conditions, Syndromes

How a SARS-CoV-2 infection can become severe COVID-19

Infection with SARS-CoV-2 leaves some people almost unaffected, while others develop life-threatening COVID-19 symptoms. So far, we do not understand exactly why symptoms and disease severity, especially in infections with ...

Diseases, Conditions, Syndromes

COVID-19 increases the chance of getting an autoimmune condition

SARS-CoV-2, the virus that causes COVID-19, can sometimes cause the immune system to mistakenly attack the person's own body. This process, known as "autoimmunity," can damage a number of different organs.

Oncology & Cancer

A little radiation goes a long way in heating up cold tumors

A Ludwig Cancer Research study conducted in both mice and a small group of patients with advanced cancers has shown that so-called "cold" tumors that are nearly devoid of immune cells—and therefore unresponsive to immunotherapy—can ...

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