Researchers from Case Western Reserve University School of Medicine and The Cleveland Clinic designed a way to screen brain tumor cells and identify potential drug targets missed by other methods. The team successfully used ...
Jul 5, 2017
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(Medical Xpress)—The protein kinase Akt is a key regulator of cell growth, proliferation, metabolism, survival, and death. New work on Akt's role in cancer stem cell biology from the lab of senior author Honglin Zhou, MD, ...
Dec 20, 2012
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Protein p53 is known for controlling the life and death of a cell and has a key role in cancer research. P53 is known to be inactive in 50 percent of cancer patients. If researchers succeed in re-establishing the presence ...
Jan 20, 2012
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Children with Down syndrome (DS) have an increased risk of developing leukemia, in particular acute megakaryoblastic leukemia (AMKL) and acute lymphoblastic leukemia (ALL). Through their studies in a mouse model of DS, a ...
Feb 22, 2012
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Altering the body's metabolism could be an effective treatment for deadly liver cancer, researchers report.
Jul 6, 2011
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The RPE and choroid, located behind the human retina, are fundamental to vision, playing a myriad of roles from light absorption to providing oxygenated blood to the photoreceptor cells. However, our understanding of the ...
Jun 1, 2023
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A novel agent that targets a mutated form of the KRAS gene—the most commonly altered oncogene in human cancers and one long considered "undruggable"—shrank tumors in most patients in a clinical trial with manageable side ...
Oct 25, 2020
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(Medical Xpress) -- The ability to control whether certain stem cells ultimately become bone cells holds great promise for regenerative medicine and potential therapies aimed at treating metabolic bone diseases.
Jul 9, 2012
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(Medical Xpress)—A team of researchers with member affiliations to institutions in the U.S. and Hong Kong, has found that researchers going after drug targets that have supporting genetic evidence could double the success ...
Treatments for Parkinson's disease, estimated to affect 1 million Americans, have yet to prove effective in slowing the progression of the debilitating disease.
Feb 7, 2012
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