News tagged with target proteins

Cancer suppressor gene links metabolism with cellular aging

The tumor suppressor protein p53 is an attractive target for drug developers. But this path has so far proven difficult, as most p53 regulatory proteins operate via protein-protein interactions, which make for poor drug targets, ...

Jan 13, 2013
popularity 3.7 / 5 (3) | comments 0 | with audio podcast

Common RNA pathway found in ALS and dementia

Two proteins previously found to contribute to ALS, also known as Lou Gehrig's disease, have divergent roles. But a new study, led by researchers at the Department of Cellular and Molecular Medicine at the University of California, ...

Sep 30, 2012
popularity 4.8 / 5 (4) | comments 0 | with audio podcast

New drug targets for squamous cell carcinoma

Researchers at Fred Hutchinson Cancer Research Center have discovered a new drug target for squamous cell carcinoma – the second most common form of skin cancer. Scientists in the laboratory of Valeri Vasioukhin, Ph.D., ...

May 19, 2011
popularity 5 / 5 (2) | comments 0 | with audio podcast

New molecules doom proteins with kiss of death

Like mobsters following strict orders, newly engineered molecules called "ubiquibodies" can mark specific proteins inside a cell for destruction – a molecular kiss of death that is paving the way for new drug therapies ...

Mar 05, 2014
popularity 5 / 5 (1) | comments 0