Cleaning up toxic 'protein clumps' could prevent dementia
The clean-up of cellular "protein clumps" could prevent the onset of some types of dementia, according to a new study from The University of Queensland.
Nov 7, 2022
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The clean-up of cellular "protein clumps" could prevent the onset of some types of dementia, according to a new study from The University of Queensland.
Nov 7, 2022
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A mechanism has been found that controls cellular levels of tau, a protein whose abnormal accumulation is at the root of tauopathies, a class of devastating neurodegenerative diseases.
Oct 21, 2022
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Early cognitive decline may result from a shift in the ratio of a protein sub-type in our brain cells triggering cell-loss. This new study, published in Scientific Reports, shows how this might be caused. The discovery provides ...
Oct 10, 2022
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Neurodegenerative disorders such as Alzheimer's and Parkinson's disease are associated with atypical proteins that form tangles in the brain, killing neurons. Neurobiologists at EPFL have now identified some key mechanisms ...
Aug 29, 2022
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Alzheimer's disease, the most common form of dementia, currently has no cure or effective therapy, in part due to gaps in our understanding of how the progressive neurodegenerative disorder arises in the brain.
Jul 6, 2022
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In order to maintain cellular homeostasis (i.e., a state of equilibrium), cells undergo selective autophagy or self-degradation of unwanted proteins. Autophagy receptors control this process, by mediating the selection of ...
Jul 1, 2022
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Ultra-powerful 7T MRI scanners could be used to help identify those patients with Parkinson's disease and similar conditions who are most likely to benefit from new treatments for previously-untreatable symptoms, say scientists.
May 16, 2022
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Children with Dravet syndrome, a severe form of epilepsy that begins in infancy, experience seizures, usually for their entire life. They are at high risk of sudden unexpected death in epilepsy (SUDEP) and can also develop ...
Apr 27, 2022
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Utilizing cutting-edge proteomics, researchers at the Buck Institute and elsewhere have mapped the "tau interactome" uncovering new findings about the role of tau in neurodegenerative disease. Publishing in Cell, scientists ...
Jan 20, 2022
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An international team led by Case Western Reserve University's School of Medicine has made a significant breakthrough in understanding why Alzheimer's disease progresses so rapidly in some people that they die within three ...
Jan 5, 2022
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