Potent antibodies neutralize HIV and could offer new therapy, study finds
(Medical Xpress)—Having HIV/AIDS is no longer a death sentence, but it's still a lifelong illness that requires an expensive daily cocktail of drugs—and it means tolerating those drugs' side effects and ...
Immunology
Nov 07, 2012 |
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Aggressive cancer exploits MYC oncogene to amplify global gene activity
Whitehead Institute researchers have determined the mechanism used by c-Myc to increase the expression of all active genes in cancer cells. Elevated levels of c-Myc are linked to increased rates of metastasis, disease recurrence, ...
Cancer
Sep 27, 2012 |
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New clue to Parkinson's: Shape of key protein surprises researchers
A new study finds that a protein key to Parkinson's disease has likely been mischaracterized. The protein, alpha-synuclein, appears to have a radically different structure in healthy cells than previously thought, challenging ...
Medical research
Aug 14, 2011 |
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Men's and women's immune systems respond differently to PTSD
Men and women had starkly different immune system responses to chronic post-traumatic stress disorder, with men showing no response and women showing a strong response, in two studies by researchers at the San Francisco VA ...
Psychology & Psychiatry
Apr 26, 2011 |
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A cautionary tale on genome-sequencing diagnostics for rare diseases
Children born with rare, inherited conditions known as Congenital Disorders of Glycosylation, or CDG, have mutations in one of the many enzymes the body uses to decorate its proteins and cells with sugars. Properly diagnosing ...
Genetics
May 10, 2013 |
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Gene variant appears to predict weight loss after gastric bypass
Massachusetts General Hospital (MGH) researchers have identified a gene variant that helps predict how much weight an individual will lose after gastric bypass surgery, a finding with the potential both to ...
Genetics
May 02, 2013 |
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Study uncovers key factor in Alzheimer's progression
(Medical Xpress)—A new study from researchers at the University of Florida may have uncovered a critical factor that drives the relentless progression of Alzheimer's disease ― a discovery that could eventually slow its ...
Alzheimer's disease & dementia
Apr 16, 2013 |
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White blood cell enzyme contributes to inflammation and obesity
Many recent studies have suggested that obesity is associated with chronic inflammation in fat tissues. Researchers at Sanford-Burnham Medical Research Institute (Sanford-Burnham) have discovered that an ...
Inflammatory disorders
Apr 02, 2013 |
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Study identifies growth factor essential to the most common malignant pediatric brain tumor
A multi-institutional team led by Massachusetts General Hospital (MGH) researchers has identified a molecular pathway that appears to be essential for the growth and spread of medulloblastoma, the most common ...
Cancer
Feb 28, 2013 |
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Kidney disease mutations found in a genomic blind spot
(Medical Xpress)—Advances in DNA sequencing technology during the past decade have given scientists powerful tools to peer into the genomes of humans and other species. Despite the efficiency and sophistication ...
Genetics
Feb 11, 2013 |
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New strategy prevents rheumatoid arthritis in mice
Dana-Farber Cancer Institute scientists have demonstrated a new strategy for treating autoimmune disease that successfully blocked the development of rheumatoid arthritis in a mouse model. They say it holds promise for improved ...
Arthritis & Rheumatism
Feb 08, 2013 |
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Calcium-binding protein mutations found in heart rhythm disorders
A team led by Vanderbilt University investigators has discovered two new genes – both coding for the signaling protein calmodulin – associated with severe early-onset disorders of heart rhythm. The findings, reported ...
Cardiology
Feb 06, 2013 |
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Researchers discover genetic basis for eczema, new avenue to therapies
(Medical Xpress)—Researchers at Oregon State University today announced the discovery of an underlying genetic cause of atopic dermatitis, a type of eczema most common in infancy that also affects millions ...
Inflammatory disorders
Dec 21, 2012 |
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Study shows antibody therapy clears Alzheimer's plaques in mice
Antibodies against amyloid beta (Aβ) protein deposits that are thought to play a role in Alzheimer's disease have shown some success in preventing the buildup of deposits in animals, but they have not been effective at removing ...
Alzheimer's disease & dementia
Dec 05, 2012 |
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Computer model enables better understanding of what happens during and after stroke
(Medical Xpress)—At the moment that someone is suffering a stroke, the immediate concern is getting them stabilized. Once the initial attack has passed, additional treatment and preventive measures can ...
Medical research
Nov 27, 2012 |
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