Therapeutic drug monitoring (TDM) refers to the principle of using blood concentrations of biopharmaceuticals to guide therapeutic decisions. EULAR—the European Alliance of Associations for Rheumatology—has developed ...
May 18, 2022
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The U.S. Food and Drug Administration approved Pluvicto (lutetium Lu 177 vipivotide tetraxetan) for treatment of adults with prostate-specific membrane antigen (PSMA)-positive metastatic castration-resistant prostate cancer ...
Apr 14, 2022
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Aducanumab, a controversial Alzheimer's disease medication with "questionable efficacy," is under review by the Therapeutic Goods Administration, but authors of a Perspective published today by the Medical Journal of Australia ...
Feb 21, 2022
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Inhibition of Ubiquitin Specific Peptidase 47 (USP47) was identified as a novel therapeutic target for hematologic malignancies bearing mutant oncoprotein EZH2, according to scientists from the Hefei Institutes of Physical ...
Jan 27, 2022
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Researchers at The University of Texas MD Anderson Cancer Center have discovered a novel function for the metabolic enzyme medium-chain acyl-CoA dehydrogenase (MCAD) in glioblastoma (GBM). MCAD prevents toxic lipid buildup, ...
May 26, 2021
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The anti-programmed death receptor 1 (PD-1) monotherapy Jemperli (dostarlimab) received approval for treatment of mismatch repair-deficient (dMMR) recurrent or advanced endometrial cancer that has progressed after treatment ...
Apr 26, 2021
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Scientists have developed a new biomaterial that regrows blood vessels and bone, potentially providing a single-stage approach when repairing large bone defects.
Apr 20, 2021
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University of Maryland School of Medicine (UMSOM) researchers have shown that psilocybin—the active chemical in 'magic mushrooms'— still works its antidepressant-like actions, at least in mice, even when the psychedelic ...
Apr 13, 2021
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Researchers from the UPC's Molecular Biotechnology Centre show that a drug for osteoporosis called raloxifene may inhibit molecules involved in the inflammatory processes associated with COVID-19.
Feb 16, 2021
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Humans are exposed to various environmental or dietary molecules that can attenuate or even increase the effect of therapeutic drugs. Studies on the industrial chemical bisphenol A and the phytoestrogen genistein, for example, ...
Dec 1, 2020
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