Alzheimer's disease & dementia

Scientists identify molecular trigger for Alzheimer's disease

Researchers have pinpointed a catalytic trigger for the onset of Alzheimer's disease – when the fundamental structure of a protein molecule changes to cause a chain reaction that leads to the death of neurons in the brain.

Immunology

Toxic cell atlas guides new therapies for neurodegeneration

A common thread in many inflammatory and neurodegenerative diseases, including multiple sclerosis (MS), is damage caused by oxidative stress. Oxidative stress occurs when cells produce toxic substances known as reactive oxygen ...

Medical research

Scientists identify most lethal known species of prion protein

Scientists from the Florida campus of The Scripps Research Institute have identified a single prion protein that causes neuronal death similar to that seen in "mad cow" disease, but is at least 10 times more lethal than larger ...

Dentistry

Bacteria in the mouth may be a cause of Crohn's disease

Crohn's disease affects four million people worldwide. The condition causes debilitating symptoms such as chronic fatigue, diarrhea, abdominal pain, weight loss and malnutrition. Once symptoms develop, Crohn's is a lifelong ...

Oncology & Cancer

Starving cancer cells of sugar could be the key to future treatment

All the cells in our bodies are programmed to die. As they get older, our cells accumulate toxic molecules that make them sick. In response, they eventually break down and die, clearing the way for new, healthy cells to grow. ...

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