Medical research

Scientists recreate DNA damage caused by toxins from smoking

Researchers from the University of York have recreated how toxins from smoking cause unique patterns of DNA damage. The discovery could help scientists better understand the cause of bladder cancer and the link to smoking.

Medical research

Engineered botox is more potent and safer in mice

Botulinum toxin (BoNT) is used for a range of applications from treating chronic pain to reducing the appearance of wrinkles, but when injected it can diffuse into the surrounding tissue and give rise to adverse effects. ...

Medical research

Study finds key mechanism for how typhoid bacteria infects

A new study has uncovered key details for how the Salmonella bacteria that causes typhoid fever identifies a host's immune cells and delivers toxins that disrupt the immune system and allow the pathogen to spread.

Diseases, Conditions, Syndromes

Why isn't there a vaccine for staph?

Staph bacteria, the leading cause of potentially dangerous skin infections, are most feared for the drug-resistant strains that have become a serious threat to public health. Attempts to develop a vaccine against methicillin-resistant ...

Medical research

Toxin responsible for Legionella growth identified

A team of scientists led by EMBL group leader Sagar Bhogaraju and Ivan Dikic of Goethe University, Frankfurt, discovered that the toxin SidJ in Legionella bacteria enforces a unique modification on human proteins and helps ...

Diseases, Conditions, Syndromes

New study uncovers weakness in C. diff toxin

A new study, led by researchers from the University of California, Irvine (UCI), uncovers the long-sought-after, three-dimensional structure of a toxin primarily responsible for devastating Clostridium difficile infection ...

Diseases, Conditions, Syndromes

Researchers discover potential antidote to botulism

Researchers have identified a compound that strongly inhibits botulinum neurotoxin, the most toxic compound known. That inhibiting compound, nitrophenyl psoralen (NPP), could be used as a treatment to reduce paralysis induced ...

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