News tagged with tumor biology
Breast cancer patients who lack RB gene respond better to neoadjuvant chemotherapy
Breast cancer patients whose tumors lacked the retinoblastoma tumor suppressor gene (RB) had an improved pathological response to neoadjuvant chemotherapy, researchers at Thomas Jefferson University Hospital and the Kimmel ...
Cancer
Jul 26, 2012 |
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Key mutations discovered for medulloblastoma -- most common childhood brain cancer
Researchers at Dana-Farber/Children's Hospital Cancer Center (DF/CHCC) and several collaborating institutions have linked mutations in specific genes to each of the four recognized subtypes of medulloblastoma, the most common ...
Cancer
Jul 22, 2012 |
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Certain heart meds may give chemo a boost
(HealthDay) -- When common heart drugs such as digitalis and digoxin are combined with some chemotherapy drugs, the effect appears to be an increase in the death of cancer cells, according to French researchers.
Cancer
Jul 18, 2012 |
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Study examines the biology of tumor-derived microvesicles
A new paper by Crislyn D'Souza-Schorey, professor of biological sciences at the University of Notre Dame, discusses the biology of tumor-derived microvesicles and their clinical application as circulating biomarkers. Microvesicles ...
Cancer
Jun 21, 2012 |
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How aging normal cells fuel tumor growth and metastasis
It has long been known that cancer is a disease of aging, but a molecular link between the two has remained elusive.
Cancer
Jun 14, 2012 |
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Breast stem-cell research: Receptor teamwork is required and a new pathway may be involved
Breast-cancer researchers at the University of Wisconsin-Madison have found that two related receptors in a robust signaling pathway must work together as a team to maintain normal activity in mammary stem cells.
Cancer
May 30, 2012 |
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Cancerous tumors deliver pro-metastatic information in secreted vesicles
Cancer researchers have known for well over a century that different tumor types spread only to specific, preferred organs. But no one has been able to determine the mechanisms of organ specific metastasis, the so-called ...
Cancer
May 29, 2012 |
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Cancer may require simpler genetic mutations than previously thought
Chromosomal deletions in DNA often involve just one of two gene copies inherited from either parent. But scientists haven't known how a deletion in one gene from one parent, called a "hemizygous" deletion, can contribute ...
Cancer
May 25, 2012 |
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Stopping cell migration may help block fibrosis and the spread of cancer
(Medical Xpress) -- Discoveries by a Yale-led team of scientists could lead the way for development of new therapies for treating fibrosis and tumor metastasis. The researchers have both uncovered a signaling ...
Medical research
May 21, 2012 |
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'Next Generation' cancer treatment ready for clinical trials
(Medical Xpress) -- A new class of anti-cancer drugs which control the growth and spread of cancers and do so with minimal side effects is being developed by researchers at the University of Sydney.
Cancer
May 18, 2012 |
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Researchers make promising discovery in pursuit of effective lymphoma treatments
Researchers at NYU School of Medicine have identified a target for slowing the progression of multiple myeloma by using currently available drugs.
Cancer
May 16, 2012 |
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Bio-hybrid device acts as 'thermostat' to control systemic inflammation in sepsis
A small, external bioreactor holding human cells pumped out an anti-inflammatory protein to prevent organ damage and other complications in a rat with acute inflammation caused by bacterial products in a model of sepsis, ...
Inflammatory disorders
May 14, 2012 |
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Research yields new clues to how brain cancer cells migrate and invade
Researchers have discovered that a protein that transports sodium, potassium and chloride may hold clues to how glioblastoma, the most common and deadliest type of brain cancer, moves and invades nearby healthy brain tissue. ...
Cancer
May 01, 2012 |
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Key protein's newly discovered form and function may provide novel cancer treatment target
Research led by St. Jude Children's Research Hospital investigators suggests that safeguarding cell survival and maintaining a balanced immune system is just the start of the myeloid cell leukemia sequence 1 (MCL1) protein's ...
Cancer
Apr 30, 2012 |
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The effects of weak magnetic fields on cancer cells and other aspects of biology
We are surrounded by a constantly changing magnetic field, be it the Earth's or those emanating from devices, such as cell phones. Carlos Martino, an assistant professor at the University of Nevada, Reno, is interested in ...
Medical research
Apr 23, 2012 |
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