News tagged with tumor biology

Genes behind aggressive endometrial cancer found

In a major breakthrough for uterine serous carcinoma (USC)—a chemo-resistant, aggressive form of endometrial cancer, Yale researchers have defined the genetic landscape of USC tumors, findings that point to new treatment ...

Jan 28, 2013
popularity 5 / 5 (1) | comments 0 | with audio podcast

Cancer biology: Keeping bad company

The p53 tumor suppressor protein manages DNA repair mechanisms in response to genetic damage and kills off precancerous cells before they multiply. The loss of p53 due to mutation greatly increases risk of ...

Jan 16, 2013
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Cancer suppressor gene links metabolism with cellular aging

The tumor suppressor protein p53 is an attractive target for drug developers. But this path has so far proven difficult, as most p53 regulatory proteins operate via protein-protein interactions, which make for poor drug targets, ...

Jan 13, 2013
popularity 3.7 / 5 (3) | comments 0 | with audio podcast

Study unmasks regulator of healthy life span

A new series of studies in mouse models by Mayo Clinic researchers uncovered that the aging process is characterized by high rates of whole-chromosome losses and gains in various organs, including heart, muscle, kidney and ...

Dec 17, 2012
popularity 5 / 5 (2) | comments 0 | with audio podcast