Oncology & Cancer

Reprogrammed macrophages promote spread of breast cancer

Metastatic breast cancer cells abuse macrophages, a type of immune cell, to promote the settlement of cancer metastases in the lungs. The reprogrammed macrophages stimulate blood vessel cells to secrete a cocktail of metastasis-promoting ...

Medical research

How the cells within breast tumors communicate with each other

An article recently published in The Journal of Clinical Investigation by the group of Dr. Maria Caffarel and Miguel Servet shows for the first time that the proinflammatory cytokine Oncostatin M (OSM) favors breast cancer ...

Oncology & Cancer

Immunotherapy delays disease progression of high-grade meningiomas

Meningiomas, tumors of the membranes (meninges) surrounding the brain and spinal cord, are the most common tumors of the central nervous system. Although most meningiomas are low grade and cause few or no symptoms, a subset, ...

Oncology & Cancer

Evolution of brain tumor classification

For more than a century, pathologists have classified and graded brain tumors, examining samples under a microscope and looking for telltale signs of tumor class and biological aggressiveness such as cell morphology, cell ...

Medications

Cholesterol-lowering drugs may slow down metastases

Cancer patients rarely die from the primary tumor, but rather from the metastases—even after successful tumor surgery. This is because cancer cells sometimes spread to other parts of body early in the disease, when the ...

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