News tagged with uncontrolled cell growth

Why cancer cells grow despite a lack of oxygen

Healthy cells reduce their growth when there is a lack of oxygen (hypoxia). This makes it even more surprising that hypoxia is a characteristic feature of malignant tumours. In two publications in the current ...

10 hours ago
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Discovery opens up possibility of slowing cancer spread

A trawl through a library of more than 50,000 'small molecules' has identified a potential candidate to inhibit the spread of cancer cells throughout the body. Reported today in the journal Nature Communications, the mo ...

Nov 12, 2014
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Cancer cells do it the "quick-and-dirty way"

(Medical Xpress)—The hallmark of cancer is uncontrolled cell growth directed by a cell cycle engine gone into overdrive. The centrepiece of this engine is the enzyme Cdc2 kinase. While Cdc2 kinase is tightly regulated in ...

Jun 11, 2014
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Melanoma of the eye caused by two gene mutations

Researchers at the University of California, San Diego School of Medicine have identified a therapeutic target for treating the most common form of eye cancer in adults. They have also, in experiments with ...

May 29, 2014
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Light triggers death switch in cancer cells

Researchers at Cardiff University have created a peptide (a small piece of protein), linked to a light-responsive dye, capable of switching 'on' death pathways in cancer cells. The peptide remains inactive until exposed to ...

Oct 16, 2013
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Gene mutation as cause of breast and ovarian cancer

A change to the so-called TERT gene considerably increases the risk of breast and ovarian cancer. This is the result of a current, multicenter study in which the University Department of Gynaecology and the ...

May 10, 2013
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