Oncology & Cancer

CRISPR-edited C. elegans identifies vulnerabilities in cancer

A one-millimeter worm, the nematode Caenorhabditis elegans, is an animal model widely used in biomedical research by hundreds of laboratories around the world. Surprisingly, it has approximately the same number of genes that ...

Neuroscience

Lab examines migraine-like phenotypes in nematode

Researchers at UMass Medical School have uncovered a mechanism that causes an imbalance in excitatory and inhibitory signaling in the nervous system. This research, which was carried out using the nematode C. elegans and ...

Medical research

New research shows how stress can weaken defenses

Research from the lab of Mark Alkema, Ph.D., professor of neurobiology, sheds light on how the "flight-or-flight" response impairs long-term organism health. The study, conducted in the nematode worm, C. elegans, a common ...

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