Archive: 02/06/2016
Repurposing an old drug to treat cystic fibrosis airway disease
The lungs contain a thin layer of fluid known as the airway surface liquid (ASL), which helps protect against pathogens. The appropriate ASL volume, pH, and ionic composition are required for optimal airway defense. Cystic ...
Jun 2, 2016
Renal dopamine signaling prevents kidney injury and improves blood pressure in mice
Dopamine signaling in the kidneys plays a critical role in blood pressure regulation and is responsible for nearly half of the salt and water excretion that occurs in response to increased dietary salt intake. Notably, genetic ...
Jun 2, 2016
Detecting an early biomarker for pancreatic cancer in blood
Pancreatic ductal adenocarcinoma is one of the most aggressive and deadliest forms of cancer. Treatment options are limited because symptoms typically do not appear until the disease is advanced and complete surgical resection ...
Jun 2, 2016
Pulmonary artery stiffening is an early driver of pulmonary hypertension
Pulmonary hypertension is an abnormal elevation of pressure in the pulmonary circulation that results in stress on the heart and remodeling of blood vessels in the lung. Pulmonary hypertension is caused by a variety of factors, ...
Jun 2, 2016