Archive: 21/04/2015
Investigational ER degrader safe, with early signs of antitumor activity against advanced ER-positive breast cancer
The new investigational estrogen receptor (ER) degrader GDC-0810 was safe and tolerable in postmenopausal women with advanced ER-positive breast cancer, and a subset of the women, all of whom were previously treated with ...
Apr 21, 2015
Phase II trial of ipilimumab-nivolumab combo shows promise in advanced melanoma
Giving the two immunotherapies ipilimumab and nivolumab simultaneously yielded better treatment responses than ipilimumab alone in patients with advanced melanoma who received no prior treatment, according to phase II clinical ...
Apr 21, 2015
Real-world targeted treatment based on whole genome sequencing difficult in pancreatic cancer
Although advances in whole genome sequencing have made it possible to identify unique druggable alterations in individual tumors, real-world application of this technology in diseases such as pancreatic cancer remains a challenge, ...
Apr 21, 2015
Caterpillar fungus could hold the key to relieving the pain of arthritis
A drug from a parasitic mushroom that lives on caterpillars could become an effective new painkiller for people with osteoarthritis within the next six years, according to UK researchers.
Apr 21, 2015
Review of whole slide imaging for pediatric specimens advances validation process
Whole slide imaging is an emerging technology that is poised to impact the practice of medicine by extending the virtual reach of pathologists. Classified as a medical device by the U.S. Food and Drug Administration, whole ...
Apr 21, 2015
New antibody-drug conjugate shows early promise for patients with metastatic HER2-positive breast cancer
An investigational antibody-drug conjugate called MM-302 was safe, tolerable, and showed signs of clinical activity in heavily pretreated patients with metastatic, HER2-positive breast cancer, according to data from a phase ...
Apr 21, 2015
New research points to elderly as growing contributor to tuberculosis in China
A major contributor to the number of tuberculosis infections and cases in China will likely be the elderly over the next few decades, requiring a refocus in efforts to control a disease affecting millions of people in the ...
Apr 21, 2015
Labels on the front of food packaging can enable healthier choices, research finds
In a new study published today in the British Journal of Nutrition, a team of researchers led by the University of Surrey, has found that front of package nutrition labels can enable consumers to make healthier food choices.
Apr 21, 2015