Oncogenic driver FGFR3-TACC3 requires 5 coiled-coil heptads for activation and disulfide bonds for stability
FGFR3-TACC3 represents an oncogenic fusion protein frequently identified in glioblastoma, lung cancer, bladder cancer, oral cancer, head and neck squamous cell carcinoma, gallbladder cancer, and cervical cancer. Various exon ...