Archive: 27/10/2016

Be your own control: Cancer sequencing differs based on genetic background of reference genome

When University of Colorado Cancer Center researcher, Jing Hong Wang, MD, PhD, found more than 1,000 genetic translocations in her mouse model of B cell lymphoma, she assumed her lab had made a mistake. To rule out experimental ...

Oct 27, 2016

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Impulsive personality linked to greater risk for early onset of meth use

Methamphetamine users who described themselves as impulsive were more likely to have started taking the drug at an earlier age, a study of more than 150 users showed.

Oct 27, 2016

Large integrated health outcomes study reveals shifting epidemiology in drug-resistant organisms

A first-of-its-kind study of 900,000 hospital admissions from an integrated health system has yielded insights into shifts in the epidemiology of multi-drug resistant organisms (MDROs) in the community.

Oct 27, 2016

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Battle hymns and lullabies: Scientist sheds light on the T cell orchestra

In research published in the prestigious journal Immunity, a Saint Louis University researcher reports new findings that help understand how the immune system's dendritic cells direct other immune cells called T lymphocytes ...

Oct 27, 2016

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Have a dental emergency? Your smartphone may soon be able to help you avoid trip to the ER

Have a dental emergency? Your smartphone may be able to help you avoid an unnecessary trip to the hospital.

Oct 27, 2016

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Normal insulin rhythm restored in mouse pancreas cells by glucose pulse

Pulses of the sugar glucose can restore normal insulin release in mouse pancreas cells that have been exposed to excess glucose, according to a study published in PLOS Computational Biology. This finding could improve understanding ...

Oct 27, 2016

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Resveratrol reverses heart damage in mice with Chagas disease

Resveratrol is the antioxidant found in red wine and famous as a food supplement capable of mimicking the effects of exercise and low calorie diets in the heart. Now Vilar-Pereira and colleagues show that treatment with resveratrol ...

Oct 27, 2016

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Stability of exhausted T cells limits durability of cancer checkpoint drugs

Checkpoint inhibitor drugs that boost the immune system to fight cancer owe part of their existence to infectious diseases. Microbes that cause diseases like HIV, malaria, and hepatitis C exploit and often activate the same ...

Oct 27, 2016

Research links senescent cells and atherosclerosis progression

Atherosclerosis is a disease in which arteries narrow due to plaques. That narrowing can lead to heart attacks and strokes—both of which are leading causes of death in the U.S. Now, in a paper published in Science, Mayo ...

Oct 27, 2016

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Research into basic workings of immune system points to way of improving therapies for cancer

In people with chronic infections or cancer, disease-fighting T cells tend to behave like an overworked militia - wheezing, ill-prepared, tentative - in a state of "exhaustion" that allows disease to persist. In a paper posted ...

Oct 27, 2016

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