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Archive
28/09/2023

Archive: 28/09/2023

Study offers way to increase immune checkpoint inhibitor effectiveness in patients with MTAP-deleted cancers

Loss of the "housekeeping" gene methylthioadenosine phosphorylase, or MTAP, is a common event in cancer. Patients with melanoma or bladder cancer whose tumor cells lack a functioning version of the gene tend not to respond ...

Sep 28, 2023

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Immune checkpoint blockade prior to surgery promising in multiple cancer types, finds study

Treating cancer with immunotherapies known as an immune checkpoint blockade (ICB) prior to surgery (so-called neoadjuvant immunotherapy) has been a rapidly growing area of research, but the scientific community is just scratching ...

Sep 28, 2023

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Research finds Paxlovid and Legevrio reduced COVID-19 hospitalization and death

New Cleveland Clinic-led research shows commonly used COVID-19 anti-viral drugs Paxlovid (nirmatrelvir) and Lagevrio (molnupiravir) reduce risk of hospitalization and death in high-risk patients with mild disease, even with ...

Sep 28, 2023

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Widespread naloxone distribution not enough to impact overdose death rate: Study

The highest ever number of opioid-related overdose deaths in the United States was recorded in 2020 at 68,630, a 68% increase in just two years. Naloxone is a medicine that can rapidly reverse an opioid overdose, but a new ...

Sep 28, 2023

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Predicting condensate formation by cancer-associated fusion oncoproteins

Many cancers are caused by fusion oncoproteins, molecules that aberrantly form when a rearrangement of DNA results in parts of two different proteins being expressed as one. Several fusion oncoproteins spontaneously form ...

Sep 28, 2023

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Brazil's diversity makes country a testing ground for a global stem cell biobank, scientists say

A biobank for all, in which a person from any background could find a bone marrow donor for a stem cell transplant, is a major goal for stem cell science. While repositories of cell lines that could be a match for most patients ...

Sep 28, 2023

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Study helps explain how COVID-19 heightens risk of heart attack and stroke

In some patients, infection with the pandemic virus SARS-CoV-2 can trigger a dangerous immune response in hardened fatty deposits (plaques) lining the heart's largest blood vessels, a new study shows.

Sep 28, 2023

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Screen-printed, flexible sensors allow earbuds to record brain activity and exercise levels

A pair of earbuds can be turned into a tool to record the electrical activity of the brain as well as levels of lactate in the body with the addition of two flexible sensors screen-printed onto a stamp-like flexible surface.

Sep 28, 2023

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Decoding the complexity of Alzheimer's disease

Alzheimer's disease affects more than 6 million people in the United States, and there are very few FDA-approved treatments that can slow the progression of the disease.

Sep 28, 2023

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Research suggests pharmacist-led intervention can improve medication adherence among Latinos with type 2 diabetes

UCLA-led research suggests that diabetes control can significantly improve for Latinos when a pharmacist implements an intervention that addresses these patients' barriers to medication adherence.

Sep 28, 2023

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