Archive: 31/08/2021

Discovery offers insight for development of cancer therapies targeting mutant p53

The tumor suppressor protein p53 is mutated in more than half of all human cancers. Several drugs that potentially can restore mutant p53 to its normal cancer-killing function are in clinical investigation.

Aug 31, 2021

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For transplants, COVID complicates the race against time

Its blue lights flashing, the ambulance races along the Madrid ring road towards the airport, the words "organ donation" clearly marked on its side, cars pulling over to let it pass.

Aug 31, 2021

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Hong Kong dismisses business pushback over 'zero-COVID' strategy

Hong Kong's leader doubled down on her zero-COVID strategy on Tuesday, brushing off growing pushback from the business community over the city's indefinite international isolation.

Aug 31, 2021

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Low-tech intervention increased participation in advanced care planning in outpatient setting

A randomized trial found that an easy-to-implement, tailored intervention increased participation in advance care planning in an outpatient setting. This is important because advance care planning, a process where a person, ...

Aug 31, 2021

Patients with multiple myeloma with the shortest survival have the most kidney damage

Nearly 20% of patients with multiple myeloma have a form in which they make extreme quantities of one component of the abnormal antibody they are producing, and these so-called "free monoclonal light chains" pile up and damage ...

Aug 31, 2021

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High vaccination levels the single most powerful determinant of college campus safety

A modeling study found that vaccination level will be the single most powerful determinant of campus safety this fall. According to the authors from Yale School of Public Health, colleges that can achieve vaccination rates ...

Aug 31, 2021

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Alcohol can cause immediate risk of atrial fibrillation

A single glass of wine can quickly—significantly—raise the drinker's risk for atrial fibrillation, according to new research by UC San Francisco.

Aug 31, 2021

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COVID-19 vaccine elicits antibodies in 90% taking immunosuppressants

COVID-19 vaccination elicited antibody responses in nearly nine out of 10 people with weakened immune systems, although their responses were only about one-third as strong as those mounted by healthy people, according to ...

Aug 31, 2021

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Researchers develop all-in-one test for the avoidance of de novo genetic disease in embryos

De novo variants (DNVs), genetic mutations that were not previously identifiable in the family history of one of two prospective parents, may cause disease in any children they have. Where a disease-causing DNV is present ...

Aug 31, 2021

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Identification of the genetic causes of childhood epilepsy shows the way to improved treatment and care

Epilepsy is one of the most common chronic neurological diseases, affecting more than 50 million people worldwide. Although it is believed that a large proportion of childhood-onset epilepsies are caused by genetic changes, ...

Aug 31, 2021

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