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06/12/2022

Archive: 06/12/2022

Expression of p-STAT3 and c-Myc correlates with P2-HNF4α expression in nonalcoholic fatty liver disease (NAFLD)

Nonalcoholic fatty liver disease (NAFLD) is associated with the metabolic syndrome and is rapidly becoming one of the major causes of hepatic cirrhosis and hepatocellular carcinoma (HCC), although some cases of HCC have ...

Dec 6, 2022

0

4

New study finds promising treatment for cognitive deficits associated with cholestatic liver disease

Patients with cholestatic liver disease such as primary biliary cholangitis (PBC) can experience significant impairment of bile flow and may develop neurological symptoms including fatigue and cognitive decline. Little is ...

Dec 6, 2022

0

7

New England college town wastewater reveals high usage of stimulants and a rise in drug use during the pandemic

The COVID-19 pandemic helped legitimize Wastewater-based Epidemiology (WBE) as a less invasive, cost-efficient way to monitor public health. WBE allows scientists to detect concentrations of drugs or biomarkers in sewage, ...

Dec 6, 2022

0

30

Black women with breast cancer may have worse outcomes than peers despite similar genetic recurrence scores

Non-Hispanic Black women with hormone receptor (HR)-positive/HER2-negative, lymph node-positive breast cancer had worse outcomes compared to non-Hispanic whites, Asians, and Hispanics, despite similar 21-gene recurrence scores, ...

Dec 6, 2022

0

3

Genomic assay may predict long-term prognosis in premenopausal patients with HR-positive early-stage breast cancer

Among premenopausal women with hormone receptor (HR)-positive, early-stage breast cancer enrolled in the SOFT trial, those with a high score on a genomic assay called Breast Cancer Index (BCI) had increased risk of distant ...

Dec 6, 2022

0

12

Racial disparity in pro-metastatic tumor microenvironment among women with residual breast cancer after NAC

Residual tumors from Black patients with estrogen receptor (ER)-positive/HER2-negative primary breast cancer treated with neoadjuvant chemotherapy (NAC) had a higher score of a biomarker of distant metastatic recurrence than ...

Dec 6, 2022

0

2

Tailored activity program shows promise for Black people with dementia and their family caregivers

Behavioral and psychological symptoms such as agitation and aggression are hallmarks of dementia that occur across disease stages and types, and can negatively impact both the person living with dementia and their caregivers. ...

Dec 6, 2022

0

4

First-line ribociclib and endocrine therapy may be more effective than combined chemotherapy in aggressive breast cancer

In patients with hormone receptor-positive, HER2-negative, advanced breast cancer—including patients with visceral crises—those treated with ribociclib plus endocrine therapy had fewer adverse events and a significantly ...

Dec 6, 2022

0

3

Itchy eyes and a runny nose? It could be climate change

Researchers with the Rutgers Environmental and Occupational Health Sciences Institute have simulated how climate change will affect the distribution of two leading allergens—oak and ragweed pollens—across the contiguous ...

Dec 6, 2022

0

60

Group exercise boosts physical, mental health for older adults, study finds

Stephen Ball has dedicated his career to improving the health of older Missourians through exercise. In 2005, he launched the University of Missouri's 'Stay Strong Stay Healthy' strength training program, which has reached ...

Dec 6, 2022

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