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Archive
08/05/2024

Archive: 08/05/2024

Team systematically modifies glyceraldehyde derivative JX22 for improved anti-heart failure efficacy and safety

Sodium-glucose cotransporter 2 inhibitors are a class of glucose-lowering drugs known for robust cardiovascular protective properties. However, the side effects induced by sodium-glucose cotransporter 2 inhibition limit application ...

May 8, 2024

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10

Research team identifies four new genetic risk factors for multiple system atrophy

In a study published in Neuron, researchers have identified four new genetic risk factors for multiple system atrophy (MSA), shedding light on this poorly understood disorder. The study, which involved collaboration from ...

May 8, 2024

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2

About 90% of US adults are on the way to heart disease, study suggests

Nine of 10 American adults are in the early, middle or late stages of a syndrome that leads to heart disease, a new report finds, and almost 10% have the disease already.

May 8, 2024

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13

Almost 30% of children and adolescents experience pain in muscles, bones or ligaments, study shows

Some 27% of Brazilian children and adolescents suffer from musculoskeletal pain of unspecified cause, according to a study reported in the Brazilian Journal of Physical Therapy. The problem is frequently underestimated by ...

May 8, 2024

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0

Researchers say future is bright for treating substance abuse through mobile health technologies

Despite the high prevalence of substance abuse and its often devastating outcomes, especially among disadvantaged populations, few Americans receive treatment for substance use disorders. However, the rise of mobile health ...

May 8, 2024

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17

New guidelines for depression care emphasize patient-centered approach in Canada

Psychiatrists and mental health professionals have a new standard for managing major depression, thanks to refreshed clinical guidelines published today by the Canadian Network for Mood and Anxiety Treatments (CANMAT).

May 8, 2024

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27

Study shows how sepsis can affect vascular smooth muscle cells on an acute and long-term basis

A recent study by University Medicine Halle shows how sepsis can lead to dysfunction of vascular smooth muscle cells. The researchers found that elevated lactate levels and acidosis, which can occur acutely during sepsis ...

May 8, 2024

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1

Discovery of key target for precision pharmacology makes ideal candidate to treat heart failure

Researchers at the University of Houston College of Pharmacy have discovered that when a higher amount of a protein called AKAP12 is present inside the heart, it speeds up the work of an enzyme called PDE8A and can accelerate ...

May 8, 2024

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0

Researchers identify what drives PARP inhibitor resistance in advanced breast cancer

Researchers at The Institute of Cancer Research, London, have increased our understanding of how a cancer drug called a PARP inhibitor stops working in women with breast cancer that has spread. This research could ultimately ...

May 8, 2024

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2

Researchers develop falls prediction model using health records to predict patients' risk of falling in the UK

Patients' risk of falling in the next 12 months could be predicted from their NHS data using a newly developed calculator.

May 8, 2024

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