A new type of immunotherapy that targets aggressive blood cancers shows promising results alongside manageable side effects, according to the results of an international Phase I/II clinical trial led by researchers at Washington ...
7 hours ago
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B-cell acute lymphoblastic leukemia (B-ALL) is the most common cancer in children, accounting for around 85% of pediatric leukemia cases. According to REDECAN, more than 400 new cases are estimated to be diagnosed in Spain ...
May 27, 2025
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The treatment of leukemia among children could be made more precise with fewer side effects with the help of more accurate methods of diagnosis. A new study led by Umeå University, Sweden, reveals that analyzing methylation ...
May 22, 2025
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A combination of two drugs could improve outcomes and reduce the need for toxic chemotherapy for B-cell acute lymphoblastic leukemia (B-ALL), the most common cancer in childhood and one that can be particularly difficult ...
May 20, 2025
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Currently, half of patients with non-Hodgkin's lymphoma and acute lymphoblastic leukemia—two types of cancer that affect blood cells—do not respond adequately to treatment with CAR-T cells. The therapy involves harvesting ...
May 19, 2025
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New research on children diagnosed with acute lymphoblastic leukemia (ALL) shows that the longer a patient's body mass index (BMI) falls within the overweight/obese category during treatment, the greater the risk of relapse ...
May 15, 2025
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Acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML) are the most common pediatric cancers and among the leading causes of death in children.
Apr 30, 2025
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Researchers in South Korea have proposed a novel cancer immunotherapy approach that could complement existing CAR-T (Chimeric Antigen Receptor T-cell) treatments. The work is published in the journal Biomarker Research.
Apr 9, 2025
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B-cell acute lymphoblastic leukemia (B-ALL) is a life-threatening and highly aggressive form of blood cancer. It is the most common childhood cancer, making up 35% of pediatric cancer cases, but it can affect people of any ...
Mar 24, 2025
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In children, can being treated for cancer have consequences for the heart—namely, cardiac arrythmias? A new study by researchers at Université de Montréal and its affiliated CHU Sainte-Justine Azrieli Research Centre ...
Feb 13, 2025
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Acute lymphoblastic leukemia (ALL) is a form of leukemia, or cancer of the white blood cells characterized by excess lymphoblasts.
Malignant, immature white blood cells continuously multiply and are overproduced in the bone marrow. ALL causes damage and death by crowding out normal cells in the bone marrow, and by spreading (infiltrating) to other organs. ALL is most common in childhood with a peak incidence at 2–5 years of age, and another peak in old age. The overall cure rate in children is about 80%, and about 45%-60% of adults have long-term disease-free survival.
Acute refers to the relatively short time course of the disease (being fatal in as little as a few weeks if left untreated) to differentiate it from the very different disease of chronic lymphocytic leukemia, which has a potential time course of many years. It is interchangeably referred to as Lymphocytic or Lymphoblastic. This refers to the cells that are involved, which if they were normal would be referred to as lymphocytes but are seen in this disease in a relatively immature (also termed 'blast') state.
This text uses material from Wikipedia licensed under CC BY-SA
