Medical research

Phat on potential, lipidomics is gaining weight

The post-holiday New Year might not seem like an ideal time to celebrate fat. But when it comes to lipids, there is no better time. For the past 15 years, scientists have been working to specify and classify these fatty acids ...

Immunology

CRISPR study reveals new immune system regulators

Scientists have created the first retroviral CRISPR-Cas9 gene editing library to explore the regulation of mouse T cells, which are key cells in the immune system. Researchers from the Wellcome Sanger Institute and their ...

Diseases, Conditions, Syndromes

How herpesviruses shape the immune system

Cytomegalovirus is widespread and remains in the body for a lifetime after infection. In healthy individuals, this virus is usually kept in check, but can become dangerous when the immune system is weakened or during pregnancy. ...

Immunology

Fighting another virus? Blame your parents

Genetics may play a bigger role in the body's disease-fighting ability than scientists previously thought, according to the results from a new study of twins in Queensland, Australia.

Medical research

Team spots clue to rare lung and kidney diseases

Pulmonary-renal syndrome (PRS) refers to a group of rare but potentially fatal conditions that nearly always are caused by a misguided attack by the body's immune system on the lungs and kidneys. Coughing up blood and blood ...

Immunology

Cell-compressing technique a new path in immunotherapy

Cell-based immunotherapies, which often involve engineering cells to activate or suppress the immune system, have delivered some dramatic results to cancer patients with few other options. But the complex process of developing ...

Immunology

Why are so many people getting a tick-borne meat allergy?

It is early morning in early summer, and I am tracing my way through the woods of central North Carolina, steering cautiously around S-curves and braking hard when what looks like a small rise turns into a narrow bridge. ...

Cancer

Cytokine levels could predict immunotherapy problems

The development of immunotherapy, which mobilizes the body's own immune system to destroy cancer cells, is one of the greatest advances in cancer treatment, but immunotherapy can cause harm to healthy tissue in some patients. ...

Surgery

Breast implant injuries hidden as patients' questions mount

To all the world, it looked like breast implants were safe. From 2008 to 2015, the U.S. Food and Drug Administration publicly reported 200 or so complaints annually—a tiny fraction of the hundreds of thousands of implant ...

Neuroscience

Auto-immune disease: The viral route is confirmed

Why would our immune system turn against our own cells? This is the question that the combined Inserm/CNRS/ Pierre and Marie Curie University/Association Institut de Myologie have strived to answer in their "Therapies for ...

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Autoimmune diseases arise from an inappropriate immune response of the body against substances and tissues normally present in the body. In other words, the immune system mistakes some part of the body as a pathogen and attacks its own cells. This may be restricted to certain organs (e.g. in autoimmune thyroiditis) or involve a particular tissue in different places (e.g. Goodpasture's disease which may affect the basement membrane in both the lung and the kidney). The treatment of autoimmune diseases is typically with immunosuppression—medication which decreases the immune response.

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